| 家兔中microRNA的研究进展 |
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| 引用本文： | 邵嘉皓,王杰,贾先波,陈仕毅,赖松家. 家兔中microRNA的研究进展[J]. 浙江农业学报, 2020, 32(1): 176-182. DOI: 10.3969/j.issn.1004-1524.2020.01.22 |
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| 作者姓名： | 邵嘉皓 王杰 贾先波 陈仕毅 赖松家 |
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| 作者单位： | 四川农业大学 动物遗传育种研究所 禽畜遗传资源发掘与创新利用四川省重点实验室,四川 成都 611130 |
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| 基金项目： | 国家现代农业产业技术体系建设专项(CARS-44-A-2); 四川省“十三五”畜禽育种攻关项目(2016NYZ0046) |
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| 摘 要： | microRNA(miRNA)是一类内源性非编码单链RNA分子,通过与靶基因mRNA配对以指导其功能表达,在动物中扮演着重要的基因调节作用。研究表明,miRNA广泛参与调节动物的生长发育、生殖调控、新陈代谢和疾病发生等生命过程。本文综述了miRNA在家兔中的研究,例如促进肌肉细胞增殖分化、调节脂肪代谢和影响疾病发生等,探讨miRNA在家兔中的研究现状和发展方向,旨在为家兔遗传育种与繁殖提供理论依据。
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| 关 键 词： | microRNA 肌肉 脂肪 疾病 家兔 |
| 收稿时间： | 2019-10-29 |
Research progress of microRNA in rabbits |
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| SHAO Jiahao,WANG Jie,JIA Xianbo,CHEN Shiyi,LAI Songjia. Research progress of microRNA in rabbits[J]. Acta Agriculturae Zhejiangensis, 2020, 32(1): 176-182. DOI: 10.3969/j.issn.1004-1524.2020.01.22 |
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| Authors: | SHAO Jiahao WANG Jie JIA Xianbo CHEN Shiyi LAI Songjia |
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| Affiliation: | Institute of Animal Genetics and Breeding, Sichuan Agricultural University/Sichuan Provincial Key Laboratory for Exploration and Innovative Utilization of Livestock Genetic Resources, Chengdu 611130, China |
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| Abstract: | microRNA(miRNA), a class of endogenous non-coding single-stranded RNA molecules, plays an important role in gene regulation in animals by pairing with target gene mRNA to guide their functional expression. Studies had shown that miRNA was widely involved in the regulation of animal growth and development, reproductive regulation, metabolism, disease occurrence and other life processes. This review summarized the studies on miRNA in rabbits in recent years, such as promoting the proliferation and differentiation of muscle cells, regulating fat metabolism and affecting the occurrence of diseases, and explored the research status and development direction of miRNA in rabbits, in order to provide theoretical basis for the breeding and reproduction of rabbits. |
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| Keywords: | microRNA muscle fat disease rabbits |
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