| 骨代谢相关血液生化指标的研究进展 |
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| 引用本文： | 杜伟,李春风,谷大海,徐志强,贾俊静,陈小波. 骨代谢相关血液生化指标的研究进展[J]. 中国畜牧兽医, 2011, 38(12): 36-40 |
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| 作者姓名： | 杜伟 李春风 谷大海 徐志强 贾俊静 陈小波 |
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| 作者单位： | 1. 云南农业大学,云南省动物营养与饲料科学重点实验室,云南昆明 650201;2. 云南省楚雄州动物疫病预防控制中心, 云南楚雄 675000;3. 云南农业大学食品科学学院,云南昆明 650201 |
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| 基金项目： | 国家自然云南，NSFC-云南联合基金项目，云南省农业厅保种经费，云南省中青年学术带头人后备人才 |
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| 摘 要： | 骨代谢包括骨合成和骨吸收两个过程。受到很多因素的影响,遗传、营养、环境、性别及内分泌等都是关键调节因素。当骨吸收过程大于骨合成过程,导致骨量流失,骨密度降低,进一步发展为骨质疏松症。骨代谢过程受到内分泌的影响,很多骨代谢血液生化指标对骨病的研究起到重要作用。近年来,国内外大量的研究报道了与骨代谢相关的血液生化指标。作者着重对血钙与血磷、甲状旁腺激素、1,25-二羟维生素D3、白细胞介素、血清总碱磷酶和骨碱磷酶等骨代谢血液生化指标对骨形成和分解的影响进行了综述。
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| 关 键 词： | 骨质疏松 骨形成 骨吸收 血液生化指标 |
| 收稿时间： | 2011-05-16 |
Study on Blood Biochemical Indicators Related to Bone Metabolism |
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| DU Wei , LI Chun-feng , GU Da-hai , XU Zhi-qiang , JIA Jun-jing , CHEN Xiao-bo. Study on Blood Biochemical Indicators Related to Bone Metabolism[J]. China Animal Husbandry & Veterinary Medicine, 2011, 38(12): 36-40 |
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| Authors: | DU Wei LI Chun-feng GU Da-hai XU Zhi-qiang JIA Jun-jing CHEN Xiao-bo |
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| Affiliation: | 1. Yunnan Key Laboratory of Animal Nutrition and Feed Science,Yunnan Agricultural Uniwersity, Kunming 650201,China;2. Animal Disease Prevention and Control Center in Yunnan Province, Chuxiong 675000,China;3. College of Food Science, Yunnan Agricultural University, Kunming 650201,China |
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| Abstract: | The bone metabolism includes the two processes of bone formation and bone resorption, which is influenced by many facters, hererity, nutrition, environment, gender and incretion are the key regulatory factors. When the bone resorption significantly exceeds formation; the activity of the osteoblasts cannot keep up with the activity of the osteoclasts, and then resulting in bone loss rapidly and bone density reducing. The process of bone metabolism is affected by incretion, many biochemical indexes of blood play an important role in the study of osteopathy. Many studies have reported biochemical parameters of blood related to bone metabolism. This paper summarize the effects of serum calcium and phosphorus, parathyroid hormone, 1,25-(OH)2D3interleukin, ALP on the bone formation and resorption. |
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| Keywords: | osteoporosis bone formation bone resorption biochemical indexes of blood |
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