| 冷应激后民猪肝素结合性表皮生长因子基因表达研究 |
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| 引用本文： | 张冬杰,刘娣,汪亮,别墅,孙洪涛,杨国伟. 冷应激后民猪肝素结合性表皮生长因子基因表达研究[J]. 中国畜牧兽医, 2011, 38(4): 98-100 |
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| 作者姓名： | 张冬杰 刘娣 汪亮 别墅 孙洪涛 杨国伟 |
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| 作者单位： | 黑龙江省农业科学院,黑龙江哈尔滨 150086 |
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| 基金项目： | "十一五"国家科技支撑计划重点项目 |
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| 摘 要： | 肝素结合性表皮生长因子(hepafin-binding epidermal growth factor-like,HB-EGF)是表皮生长因子(epidermal growth factor,EGF)家族的成员之一。本研究采用Real-time PCR分析了在民猪冷诱导后该基因在骨骼肌内的表达变化情况。结果表明,低温组(－20 ℃)的HB-EGF基因的表达水平与常温组(10 ℃)相比出现了极显著下降(P＜0.01)。据此推测,冷应激抑制了HB-EGF基因的表达,也间接抑制了民猪的正常生长。
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| 关 键 词： | 民猪 冷应激 HB-EGF Real-time PCR |
| 收稿时间： | 2010-09-19 |
Study on Expression of Min Pig Hepafin-binding Epidermal Growth Factor-like Gene in Cold Stress |
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| ZHANG Dong-jie,LIU Di,WANG Liang,BIE Shu,SUN Hong-tao,YANG Guo-wei. Study on Expression of Min Pig Hepafin-binding Epidermal Growth Factor-like Gene in Cold Stress[J]. China Animal Husbandry & Veterinary Medicine, 2011, 38(4): 98-100 |
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| Authors: | ZHANG Dong-jie LIU Di WANG Liang BIE Shu SUN Hong-tao YANG Guo-wei |
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| Affiliation: | Heilongjiang Academy of Agricultural Sciences, Harbin 150086, China |
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| Abstract: | Hepafin-binding epidermal growth factor-like (HB-EGF) is one of the epidermal growth facto family. In this study, Real-time PCR method was used to detect and analysis the expression of HB-EGF gene in Min pig skeletal muscle after cold-induced. The results showed that the low-temperature group(－20 ℃) of HB-EGF gene expression levels compared with the normothermia group (10 ℃) appeared very significantly decreased (P＜0.01). As above, cold stress inhibits the expression of HB-EGF gene, but also indirectly inhibit the normal growth of Min pig. |
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| Keywords: | Min pig cold stress HB-EGF Real-time PCR |
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