| 西藏阿里地区冰川棘豆毒性生物碱的鉴定 |
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| 引用本文： | 谭远友,王建华,李勤凡,洪子鹂,高巨星,郭庆宏.西藏阿里地区冰川棘豆毒性生物碱的鉴定[J].畜牧与兽医,2002,34(5):12-13. |
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| 作者姓名： | 谭远友 王建华 李勤凡 洪子鹂 高巨星 郭庆宏 |
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| 作者单位： | 1. 西北农林科技大学,陕西,杨凌,712100
2. 陕西省畜牧兽医总站,陕西,西安,710014 |
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| 基金项目： | 陕西省援藏课题（0060C8） |
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| 摘 要： | 光谱分析表明冰川棘豆生物碱结晶Ⅰ为含有1分子结晶水的2,2,6,6-四甲基-4哌啶酮（2,2,6,6-tetramethyl-4-piperidone,TMPD）。小鼠口服LD50为935.4 mg/kg,95％可信限为852.7～1021.4 mg/kg。小鼠TMPD急性中毒症状与山羊冰川棘豆自然中毒症状基本相似。
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| 关 键 词： | 冰川棘豆 疯草 生物碱 2 2 6 6-四甲基-4-哌啶酮 毒性 |
| 文章编号： | 0529-5130(2002)05-0012-02 |
Identification of the alkaloid isolated from glacial crazywccd ( Oxytropis glacialis Benth ex Bye) in Ali prefecture in Tibet |
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| TAN Yuan-you,WANG Jian-hua,LI Qing-fan,HONG Zhi-li,GAO Ju-xing,GUO Qing-hong.Identification of the alkaloid isolated from glacial crazywccd ( Oxytropis glacialis Benth ex Bye) in Ali prefecture in Tibet[J].Animal Husbandry & Veterinary Medicine,2002,34(5):12-13. |
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| Authors: | TAN Yuan-you WANG Jian-hua LI Qing-fan HONG Zhi-li GAO Ju-xing GUO Qing-hong |
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| Abstract: | The alkaloid crystal I isolated from glacial crazyweed ( Oxytropis glacialis Benth ex Bye) in Ali prefecture in Tibet was identified as 2,2,6,6-tetramethyl-4-piperidone (TMPD) with infrared spectrophotometer, nuclear magnetic resonance spectrophotometer and data base system. Its oral LD50 was 935.4 mg/kg with 95% possibility of 852.7-1 021.4 mg/kg. The mice poisoned by TMPD showed the same symptomes as the sheep poisoned by glacial crazyweed. |
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| Keywords: | Oxytropis glacialis crazyweed alkaloid 2 2 6 6-tetramethy1-4-piperisdone toxicity |
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