钼对羊的中毒性试验

选择杂交波尔山羊8只, 小尾寒羊2只(4组), 分为5组, 前四组每日依次灌服150、100、60、100mg的钼(Na2MoO4·2H2O), 5d后剂量减半; 5组灌自来水。试验45d。结果表明: 试验羊出现磨牙、咳嗽、呻吟、跛行、腹泻及贫血等明显的临床症状。各试验组RBC、Hb和PCV均显著低于对照组; 1组RBC、MCV、MCH极显著低于3组(P<0 01); 4组PCV、MCV、MCH极显著低于2组(P<0 01 ), Hb显著低于2组(P<0 05)。剖检表明, 试验组羊尸体消瘦, 血液稀薄; 肝脏肿大且发生脂肪变性; 肾脏体积肿大, 肾小管上皮细胞肿胀; 肠黏膜肿胀、出血, 小肠壁有红白相间的花斑样病理变化。

Toxic trails of molybdenum in Boergoat and sheep

Eight crossed Boergoats were allocated to group1,2,3 and 5 (control) and two sheep as group 4. Groups 1,2,3 and 4 received additional molybdenum at dosage of 150 mg, 100 mg, 60 mg and 100 mg molybdenum (Na 2MoO 4·2H 2O) by oral route for 5 days, then received half of molybdenum respectively for 40 days, and the control group was given only water. The results were as fellow: Boergoats and sheep in the tested groups (1,2,3,4) obviously presented cough, groan, staggering gait, inappetance, depression, diarrhea and anaemia. The concentration of red blood cell (RBC), hemoglobin (Hb) and the packed cell volume (PCV) in tested groups were significantly lower than the control's. RBC, MCH and MCV of group 1 were extremely significant lower than group3's (P<0.01), Hb of group 4 was significantly lower than group2's (P<0.05), and PCV, MCH and MCV were extremely significant lower than group 2's (P<0.01); From necropsy, livers and kidneys presented swelled, and intestine wall araised hyperemia and hemorrhage.