紫锥菊对传染性法氏囊疫苗免疫效果的影响

为了探讨紫锥菊作为免疫增强剂的免疫效果和机理,本试验用1日龄的罗斯308肉鸡作为试验材料并用传染性法氏囊疫苗进行免疫。紫锥菊提取物分3种剂量组(A组0.1 mL/只、B组0.5 mL/只、C组1 mL/只)在6日龄开始连续给雏鸡口服7 d,在13,20,27,34,41日龄采血检测外周血中法氏囊病毒抗体,同时测定外周血中IL-2和TNF-α的含量,计算肉鸡的生产性能。结果表明,紫锥菊提取物能明显提高鸡外周血中法氏囊病毒抗体滴度,以及细胞因子IL-2和TNF-α含量,并能改善肉鸡的生产性能。所用3个剂量组中,以B组的0.5 mL/只为最佳的用药剂量。说明紫锥菊提取物具有明显的免疫促进作用。

Effects of Echinacea purpurea extracts on immunological response to IBDV vaccine in broilers

To explore the immune regulation role of Echinacea purpurea,1-day-old broiler of Ross 308 were vaccinated with infectious bursal disease(IBD) vaccine.At 6 day old three experimental groups were given orally Echinacea purpurea extracts with the different dosages(A group 0.1 mL,B group 0.5mL,C group 1mL) and continued for 7 days.On 13th,20th,27th,34th and 41th days the antibody levels to IBDV,contents of IL-2 and TNF-α,and performances were determined.The results showed that application of Echinacea purpurea extracts could significantly increase the IBDV antibody levels,IL-2 and TNF-α contents in the blood and improve performances of broilers.The best result was achieved in the 0.5 mL dosage group.It suggested that the Echinacea purpurea has an obvious immune regulation effect.