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单诺沙星对人工诱发鸡大肠肝菌病的药效试验
引用本文:曾振灵,刘建新,王志强,叶启薇.单诺沙星对人工诱发鸡大肠肝菌病的药效试验[J].畜牧与兽医,2000,32(3):17-18.
作者姓名:曾振灵  刘建新  王志强  叶启薇
作者单位:1. 华南农业大学动物医学系,广东,广州,510642
2. 华南农业大学动物科学系
摘    要:根据试管 2倍稀释法测定的单诺沙星及氯霉素对鸡大肠杆菌的最小抑菌浓度 ,对实验性大肠杆菌病鸡进行内服给药 (每隔 12h给药 1次 ,连续 3d)治疗试验。结果表明 ,单诺沙星及氯霉素对鸡大肠杆菌的最小抑菌浓度分别是 0 0 5及 1 6mg/L。单诺沙星以 5mg/kg、氯霉素以40mg/kg的剂量给鸡内服后 ,对大肠杆菌病的治愈率分别为 87 5%及 55 0 %。

关 键 词:单诺沙星  氯霉素  大肠杆菌病  

Effect of danofloxacin on experimental colibacillosis in chicken
ZENG Zhen-ling,LIU Jian-xin,WANG Zhi-qiang,YE Qi-wei.Effect of danofloxacin on experimental colibacillosis in chicken[J].Animal Husbandry & Veterinary Medicine,2000,32(3):17-18.
Authors:ZENG Zhen-ling  LIU Jian-xin  WANG Zhi-qiang  YE Qi-wei
Abstract:Minimal inhibitory concentrations(MICs)of danofloxacin and chloramphenicol were determined in vitro for Escherichia coli by two fold dilution method .The treatment test on experimental colibacillosis of chicken were performed with danofloxacin(5 mg/kg)and chloramphenicol(40 mg/kg)by oral administration twice daily for 3 successive days.The results showed that the MICs of danofloxacin and chloramphenicol were 0 05 and 1 6 mg/L for E.coli,respectively.The curative rates of the drugs against colibacillosis were 87 5% and 55 5%,respectively.
Keywords:danofloxacin  chloramphenicol  colibacillosis  chicken
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