| 氯苯胍在鸡组织中的残留消除规律研究 |
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| 引用本文： | 班付国,吴宁鹏.氯苯胍在鸡组织中的残留消除规律研究[J].中国兽药杂志,2012,46(11):24-26. |
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| 作者姓名： | 班付国 吴宁鹏 |
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| 作者单位： | 河南省兽药监察所,郑州,450008 |
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| 摘 要： | 采用超高效液相色谱一串联质谱法（UPLC-MS／MS）研究了氯苯胍在鸡组织中的残留消除规律。白来杭鸡以含氯苯胍500mg／kg饲料饲喂7d，停药后的第0、1、3、5、7天取其肌肉、肝脏、肾脏、皮和脂肪五种组织，采用UPLC-MS／MS法测定其残留状况。结果表明，氯苯胍在肌肉中残留量较小，代谢消除比较快，2d后未检出；而在脂肪、皮和肝脏中残留量较大，代谢消除较慢。
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| 关 键 词： | 氯苯胍 鸡组织 残留消除 |
| 收稿时间： | 5/17/2012 4:20:06 PM |
| 修稿时间： | 7/4/2012 12:00:00 AM |
Depletion of Robenidine Residue in Chicken Tissues |
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| Institution: | Henan Institute of Veterinary Drug Control, |
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| Abstract: | The depletion of robenidine residue in chicken tissues was studied by UPLC - MS/MS. After an oral dose of 500 mg per kilogram of robenidine for 7 days, the robenidine residue in chicken muscle was lower than that in other tissues, such as the fat, skin, kindey and liver, and it was not detected after 2 days. The results showed that robenidine in chicken tissues was of rapid absorption, and hard to be eliminate. |
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| Keywords: | robenidine chicken tissues residue depletion |
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