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溶菌酶治疗兔大肠杆菌病的研究
引用本文:季权安,鲍国连.溶菌酶治疗兔大肠杆菌病的研究[J].中国兽药杂志,2012,46(4):20-21.
作者姓名:季权安  鲍国连
作者单位:浙江省农业科学院畜牧兽医研究所,杭州,310021
基金项目:1、国家现代农业兔产业技术体系疾病预防与控制岗位(CARS-44-C-2);2、浙江省公益性技术应用研究计划项目“实验兔巴氏杆菌病PCR快速诊断新技术研究与应用”(2011C37085)
摘    要:为了有效控制兔大肠杆菌病,开展了溶菌酶临床治疗研究。用溶菌酶对160例经实验室确诊为大肠杆菌病的病兔进行临床治疗对比试验,按患兔症状轻重均匀搭配分为4组,每组40只,溶菌酶组拌料饲喂,4 d为一疗程,与丁胺卡那霉素、氨苄青霉素、氟哌酸组进行疗效比较试验,结果治疗有效率达95%以上,比对照组的治愈率平均高50个百分点。试验表明溶菌酶疗效显著,为治疗兔大肠杆菌病提供了科学依据,对兽医临床用药具有一定的指导意义。

关 键 词:溶菌酶    大肠杆菌
收稿时间:10/3/2011 8:36:31 PM
修稿时间:2011/10/14 0:00:00

The research on treatment effect of Lysozyme with colibacillosis in rabbit
JI Quan-an,WEI Qiang,XIAO Chen-wen,LIU Yan,BAO Guo-lian.The research on treatment effect of Lysozyme with colibacillosis in rabbit[J].Chinese Journal of Veterinary Drug,2012,46(4):20-21.
Authors:JI Quan-an  WEI Qiang  XIAO Chen-wen  LIU Yan  BAO Guo-lian
Institution:Institute of Animal Husbandry and Veterinary Science, Zhejiang Academy ofAgricultural Sciences,
Abstract:Lysozyme, an enzyme which could disolve the outmembrame of bacteria selectively is protective for the biosome itself. Rabbit colibacillosis is one kind of enteropatia which could induce the quick outbreak and high mortality within neonatal rabbit. The clinlcal symptom of the disease include water like or jelly like diarrhea so as the died of dehydration. The current study used lysozyme to treat 40 rabbit- colibacillosis, ninety-five percent of rabbits were cured, fifty percent higher than amikacin, norfloxacin and ampicillin averagely. The medicine was applied in many places totally 2 million rabbits successfully.
Keywords:lysozyme  rabbit  Escherichia coli
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