头孢噻呋对实验性感染鸡白痢沙门氏菌病的药效学研究

研究了头孢噻呋对实验性感染鸡白痢沙门氏菌的防治效果。结果显示，头孢噻呋体内疗效良好，治疗组与预防组的治愈率、有效率、相对增重率均不同程度高于感染对照组（P〈0.05或P〈0.01）；头孢噻呋的治疗效果高剂量组与中剂量组无显著差异（P〉0．05），高剂量组与低剂量组差异显著（P〈0．05）；头孢噻呋的中剂量组与头孢曲松、氨苄西林组的疗效相比均差异显著（P〈0．05或P〈0．01）。实验结果表明，头孢噻呋按0．1mg／只的剂量肌肉注射，每日一次，可对鸡白痢沙门氏菌病起到有效的防治效果。

Pharmacodynamical Studies of Ceftiofur in Chickens Experimentally Induced with Salmonella pullorum

This paper described the pharmacodynamical studies of ceftiofur in chicken experimentally induced with S.pullorum. The results showed that ceftiofur had excellent therapeutic effects on this infection. The healing rate, effective rate and relative weight gain rate of all experiment groups were obviously better than those of positive control group(P<0.05 or P<0.01). The high dose of ceftiofur showed the similar therapeutic effects with the middle dose (P>0.05)and excellent effects than the low dose (P<0.05). Comparing with ceftriaxone and ampicillin, the middle dose of ceftiofur could effectively cure the disease (P<0.05 or P<0.01). According to the results of the experiment, chicken injected with the middle dose of ceftiofur could prevent the disease.