| 盐酸阿苯达哩亚砜化学结构分析 |
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| 引用本文： | 刘志亮.盐酸阿苯达哩亚砜化学结构分析[J].中国兽药杂志,2011,45(3):48-51. |
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| 作者姓名： | 刘志亮 |
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| 作者单位： | 青岛信得科技股份有限公司 |
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| 基金项目： | 国家科技支撑计划（2006BAD31B04）经济型新化学合成药的研制与应用 |
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| 摘 要： | 建立了药物盐酸阿苯达唑亚砜的化学结构确证方法.通过高效液相色谱(HPLC)测定盐酸阿苯达唑亚砜纯度,采用紫外光谱(UV)、红外光谱(IR)、核磁共振(NMR)以及质谱(MS)等分析方法对盐酸阿苯达唑亚砜样品进行了结构测定.结果确证盐酸阿苯达唑亚砜的结构为5-(丙亚砜基)-1H-苯并咪唑-2-基]氨基甲酸甲醋盐酸.本方...
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| 关 键 词： | 盐酸阿苯达唑亚砜 结构测定 |
| 收稿时间： | 2010/10/25 0:00:00 |
| 修稿时间： | 2010/11/25 0:00:00 |
Chemical structure analysis of Albendazol sulfoxide hydrochloride |
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| liuzhiliang.Chemical structure analysis of Albendazol sulfoxide hydrochloride[J].Chinese Journal of Veterinary Drug,2011,45(3):48-51. |
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| Authors: | liuzhiliang |
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| Institution: | Shandong Sinder Technology corporation |
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| Abstract: | Objective: To establish a method for the determination of the chemical structure of Albendazol sulfoxide hydrochloride. Method: High - performance liquid chromatography (HPLC), ultraviolet spectroscopy(UV) , infrared Fourier transform spectroscopy ( FT - IR) , nuclearmagnetic resonance (NMR) , mass spectroscopy(MS) were adopted to analyze the chemical structure of Albendazol sulfoxide hydrochloride. Result: The chemical structure is Methyl 5-(propylsulfinyl)-2-benzimidazolecarbamate* Hydrochloric acid. Conclusion: The result of the method is accurate, general and can provide a comp rehensive reference for production and identification of Albendazol sulfoxide hydrochloride. This article has reasonable experiment design, reliable data, and accurate result, so it has high theory value and practical value. |
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| Keywords: | Albendazol sulfoxide hydrochloride chemical structure analysis |
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