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| 禽源沙门菌对四环素的耐药性及耐药基因调查分析 | |
| 引用本文： | 张纯萍,宁宜宝,宋立,陈惠娟,陈瑞.禽源沙门菌对四环素的耐药性及耐药基因调查分析[J].中国家禽,2011,33(3). |
| 作者姓名： | 张纯萍 宁宜宝 宋立 陈惠娟 陈瑞 |
| 作者单位： | 1. 中国兽医药品监察所,北京,100081 2. 扬州大学,江苏扬州,225009 3. 华南农业大学,广东广州,510642 |
| 基金项目： | 北京市科技新星计划项目，2009-2010年度农业部动物源细菌耐药性监测计划项目 |
| 摘 要： | 为了更好地了解禽源沙门菌对四环素的耐药性及耐药基因分布,从不同来源的家禽样品中分离沙门菌,调查其对四环素的耐药性以及耐药菌株中8种四环素耐药基因tet(A)、tet(B)、tet(C)、tet(W)、tet(M)、tet(D)、tet(K)和tet(L)]的携带情况.结果表明,18.8%的沙门菌分离株对四环素耐药,健康成鸡分离株对四环素的耐药性明显高于雏鸡、死胚或病禽分离株;四环素耐药株中tet(A)、tet(B)和tet(M)基因的携带比例分别为73.1%、11.5%和3.8%,说明沙门菌对四环素的耐药机制以tet(A)和tet(B)基因介导的主动外排为主.本研究首次在对四环素耐药的沙门菌中检测到tet(M)基因,说明tet(M)基因在沙门菌对四环素的耐药性方面也具有潜在的作用. |
| 关 键 词： | 沙门菌 四环素 耐药性 四环素耐药基因 |
Investigation of Resistance to Tetracycline and Distribution of Tetracycline Resistance Genes of Salmonella Isolates from Poultry |
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| ZHANG Chunping,NING Yibao,SONG Li,CHEN Huijuan,CHEN Rui.Investigation of Resistance to Tetracycline and Distribution of Tetracycline Resistance Genes of Salmonella Isolates from Poultry[J].China Poultry,2011,33(3). | |
| Authors: | ZHANG Chunping NING Yibao SONG Li CHEN Huijuan CHEN Rui |
| Institution: | ZHANG Chunping1,NING Yibao1,SONG Li1,CHEN Huijuan2,CHEN Rui3(1.China Institute of Veterinary Drug Control,Beijing 100081,2.Yangzhou University,Yangzhou,Jiangsu 225009,3.South China Agricultural University,Guangzhou,Gunagdong 510642) |
| Abstract: | In order to better understand antimicrobial susceptibility to tetracycline and distribution of tetracycline resistant genes of Salmonella in poultry,resistance to tetracycline of the isolats which were from poultry samples of different origins and 8 tetracycline resistance genes tet(A),tet(B),tet(C),tet(W),tet(M),tet(O),tet(K)and tet(L)]among tetracycline-resistant Salmonella isolates were detected.The results showed that 18.8% of isolates were resistant to tetracycline.Higher resistance rate was observed ... |
| Keywords: | Salmonella tetracycline drug resistance tetracycline resistance genes |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |