铜对奶牛免疫能力的影响

目的]检测实验奶牛血清中的微量元素铜的水平及相关指标的变化规律。方法]实验所用实验动物均选自黑龙江地区某奶牛场,常规水平饲养管理,TMR全混合日粮自由采食。根据DHI数据随机选择体重、胎次(2~3次)、泌乳期(0~10d)、体况和饲养管理高度相似的泌乳奶牛50头。结果]实验奶牛血清铜水平与IL-2的相关性为R=0.355,显著性为P=0.011。实验奶牛血清铜水平与IL-2呈显著正相关,泌乳奶牛血清中的IL-2会随着铜水平的升高而有所升高。实验奶牛血清铜水平与IL-1的相关性为R=0.215,显著性为Ρ=0.133,P>0.05。实验奶牛血清铜水平与IL-1不相关。实验奶牛血清铜水平与TNF-α的相关性为R=0.185,显著性为P=0.198,P>0.05。结论]实验奶牛血清铜水平与TNF-α不相关。

Effect of Copper on Immune Ability of Dairy Cows

Objective]To detect the serum level of trace element of copper in experimental dairy cows and to characterize the variation rule of related indexes.Method]The experimental dairy cows used in this study were selected from a dairy farm in Heilongjiang Province,and were reared under free-choice feeding system with TMR diets.According to the DHI data,50 lactating cows with similar body weight,parity (2-3 times),lactation period (0-10 days),body condition and feeding management were randomly selected.Result]The correlation between serum copper level and IL-2 content in the experimental dairy cows was R=0.355,P=0.011.There was a significantly positive correlation between serum copper level and IL-2 content in the experimental dairy cows.The serum content of IL-2 in the lactating dairy cows was increased with the elevation of serum copper level.The correlation between serum copper level and IL-1 content in the experimental dairy cows was R=0.215,and the significance was P=0.133,P>0.05.There was no correlation between serum copper level and IL-1 content in the experimental dairy cows.The correlation between serum copper level and TNF- alpha content in the experimental dairy cows was R=0.185,with a significant difference of P=0.198,P>0.05.Conclusion]There was no correlation between serum copper level and TNF-alpha content in experimental dairy cows.