抗白羽肉鸡传染性法氏囊病中草药复方制剂的开发及应用

为了研究不同中草药复方制剂对肉鸡传染性法氏囊病的预防和治疗效果，将5 600只健康白羽肉鸡平均分为两大组，即预防试验组和治疗试验组；利用经中药筛选试验获得的6个复方制剂开展鸡传染性法氏囊病的预防和治疗试验，其中，配方Ⅰ-Ⅲ用于预防试验，配方Ⅳ-Ⅵ用于治疗试验；采用拌料给药、饮水给药、雾化给药、综合给药4种方法分别开展预防和治疗试验，每种方法分别设置5个小组，包含3个试验组和2个对照组，每个试验组应用1种中草药复方制剂。预防试验主要观察肉鸡发病率和死亡率，治疗试验主要观察肉鸡治愈率及死亡率。结果表明：在预防试验中，配方Ⅱ在4种试验方法中的整体表现最佳，其预防效果与接种疫苗的预防效果相近，给予配方Ⅱ的肉鸡在4种试验方法中的发病率均在20%以下；在治疗试验中，配方Ⅴ的综合治疗效果最佳，在利用饮水给药和综合给药方法时，其治愈率与给予抗生素和抗病毒药物的对照组相近，且从总体来看，各配方在饮水给药治疗和综合治疗方法中的治疗效果明显优于拌料给药治疗和雾化给药治疗。综上表明，天然中草药复方制剂具有一定的预防和治疗肉鸡传染性法氏囊病的功效。

Development and Application of Compound Traditional Chinese Medicine against Chicken Infectious Bursa Disease in White Feather Broiler

The aim of the present study was to evaluate the preventive and therapeutic effects of compound traditional Chinese medicines with different administrative methods against chicken infectious bursa disease （IBD） in broilers. A total of 5 600 healthy white feather broilers were chosen and averagely assigned into preventive experiment group and therapeutic experiment group; six screened compound traditional Chinese medicines were used in preventive experiment （compound Ⅰ-Ⅲ） and therapeutic experiment （compound Ⅳ-Ⅵ）; a total of four administrative methods, including feeding administration, drinking administration, atomization administration and comprehensive administration, were used in both preventive experiment and therapeutic experiment; there were five groups for each administrative method, including three experimental groups and two control groups, and one compound traditional Chinese medicine was administrated for each experimental group; the morbidity and mortality of the broilers caused by IBD were observed in preventive experiment, and the healing rate and mortality of the broilers caused by IBD were observed in therapeutic experiment. The results showed that in preventive experiment, the compound Ⅱ had an overall good performance in all of the four administrative methods; the preventative efficacy of compound Ⅱ against IBD was similar to that of vaccination; the IBD incidence of the broilers administrated with compound Ⅱ by the four administrative methods were all below 20%; in therapeutic experiment, the best comprehensive curative effect was observed in compound Ⅴ; when the IBDV challenged broilers were given compound Ⅴ by drinking administration method and comprehensive administration method, the healing rate was similar rate to that of the broilers treated with antibiotics＋antiviral agents; generally, for all of the three compound traditional Chinese medicines for therapeutic use, drinking administration method and comprehensive administration method had better curative effect compared to feeding administration method and atomization administration. The combined data suggested that the natural compound traditional Chinese medicine had certain preventive and therapeutic effects against IBD in broilers.