Inactivated bluetongue virus vaccine in lambs: Differential serological responses related to breed |
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| Authors: | L J Berry B I Osburn J L Stott T Farver B Heron W Patton |
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| Institution: | (1) Department of Food and Agriculture, State of California, Bureau of Animal Health, Sacramento, California;(2) School of Veterinary Medicine, University of California, Davis, California;(3) California State University, Chico, California, (USA) |
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| Abstract: | A mixed breed flock of lambs, consisting of Suffolks, Hampshires, Columbias and Finnish breeds, were vaccinated with binary ethylenimine inactivated bluetongue virus (BTV) serotypes 11, 17 and a mixture of 11 and 17 in aluminum hydroxide. Agar gel precipitin antibodies were used as an indicator of immunity. Sero-conversion of Hampshires and Suffolk lambs was poor at 43% as compared to 84% in the Columbia and Finn lambs. These results indicate a breed difference in immunological response to inactivated BTV vaccine. |
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