Distribution of leucocyte antigens in Icelandic horses affected with summer eczema compared to non-affected horses |
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Authors: | S Halldórsdóttir S Lazary E Gunnarsson H J Larsen |
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Institution: | Norwegian College of Veterinary Medicine, Department of Microbiology and Immunology, Oslo. |
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Abstract: | Three hundred and three horses, exported from Iceland to Norway, Sweden, Denmark, Switzerland or Germany were tested for their distribution of leucocyte antigens. One hundred and thirty-six horses were affected with summer eczema. The panel of sera recognised the internationally accepted ELA-specificities A 1 to A10, and the nine work shop specificities W 11 to W 15 and W 18 to W 21. Also, some local specificities, characterised in Switzerland (Be I, Be III, Be 8, Be 25, Be 26, Be 27), and two non major histocompatibility complex (MHC)-linked antigens (Ely 1:1, Ely 2) were included. Only one antigen, Be 8, gave a statistically significant difference in distribution between the two populations: Relative risk = 2.5, x2 = 10.11, corrected P less than 0.01. |
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