Pharmacokinetics of gamithromycin after intravenous and subcutaneous administration in pigs |
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| Authors: | H Wyns E MeyerE Plessers A WatteynS De Baere P De BackerS Croubels |
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| Institution: | Department of Pharmacology, Toxicology and Biochemistry, Ghent University, Faculty of Veterinary Medicine, Salisburylaan 133, 9820 Merelbeke, Belgium |
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| Abstract: | The aim of this study was to investigate the pharmacokinetic properties of gamithromycin in pigs after an intravenous (i.v.) or subcutaneous (s.c.) bolus injection of 6 mg/kg body weight. The plasma concentrations of gamithromycin were determined using a validated high-performance liquid chromatography–tandem mass spectrometry method, and the pharmacokinetics were noncompartmentally analysed. |
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| Keywords: | Gamithromycin Pharmacokinetics Pig Absolute bioavailability Subcutaneous |
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