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Tuberculosis in domestic animal species
Institution:1. Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy;2. VISAVET Health Surveillance Centre, Universidad Complutense Madrid, 28040 Madrid, Spain;3. Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA;4. National Reference Centre for Bovine Tuberculosis, Istituto Zooprofilattico Sperimentale della Lombardia e dell''Emilia Romagna, Brescia, Italy;5. Istituto Zooprofilattico Sperimentale dell''Umbria e delle Marche, Perugia, Italy;6. Istituto Zooprofialttico Sperimentale della Sicilia, Barcellona Pozzo di Gotto, Messina, Italy;7. FAO Reference Centre for Veterinary Public Health, Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy;1. Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA;2. Centro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense Madrid, Avda. Puerta de Hierro S/N, 28040 Madrid, Spain;3. Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Avda. Puerta de Hierro S/N, 28040 Madrid, Spain;1. Animal Health and Veterinary Laboratories Agency – Wyebridge, Addlestone, Surrey, UK;2. Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, Edifici CReSA, Bellaterra, 08193 Catalonia, Spain;3. AgResearch, Hopkirk Research Institute, Palmerston North, New Zealand;1. MAEVA SERVET SL, C/ de la Fragua 3, 28749, Alameda del Valle, Madrid, Spain;2. Centro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense, Avda. Puerta de Hierro s/n, 28040, Madrid, Spain;3. Prionics AG, Wagistrasse 27A, 8952 Schlieren-Zürich, Switzerland;4. INGENASA, C/ Hermanos García Noblejas 39, 28037, Madrid, Spain;5. Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain
Abstract:M. bovis and M. caprae, members of the Mycobacterium tuberculosis complex (MTC), are the major causative agents of tuberculosis in domestic animals. Notably, M. bovis exhibits a wide host range; the infection has been reported in many domesticated animals and free or captive wildlife. Despite most of them acting as spill-over hosts in particular epidemiological scenarios, some domesticated species as pigs, camelids and goats may display high rates of infection and possibly play a role in the inter-species transmission of the disease. The aim of this review is to make an updated overview of the susceptibility and the role in the transmission of the disease of the most common domesticated animals species such as small ruminants, pigs, horses, camelids, dogs and cats. An overview of the diagnostic approaches to detect the infection in each of the species included in the review is also presented.
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