鸡源大肠埃希氏菌部分生物学特性研究

对从天津地区分离到的71株鸡大肠杆菌的部分生物学特性包括致病性、血清型、耐药特性和免疫原性等进行了研究。结果表明其中60株为致病性菌株,占分离菌株的84.5%;60个致病性菌株共定型出45个菌株,分属O1、O2、O5、O6、O20、O45、O53、O74、O75、O78、O88、O89、O92、O107、O111、O145等16个血清型,其中O78、O88、O2、O45、O53和O145为优势血清型,占定型菌株的73.4%;试验菌株具有广泛的耐药性,60个致病性菌株均为多重耐药。免疫原性测定试验结果表明,O2、O78、O88血清型菌株均可对相同血清型菌株提供很好的保护,但3个血清型菌株之间缺乏有效的保护。

Studies on Some Biological Characteristics of Chicken Escherichia coli

strains of E.coli isolated from chickens of fowl farms in Tianjin regions were studied with respect to their biological characteristics,including pathogenicity for1-week -old chick,O serogroups identification,immunogenicity detection and antibiotic sensitivity.The results showed that 60of the71strains of chicken E.coli were pathogenic strains,and that 45of the60strains of pathogenic E.coli were identified as O type belonged to16serogroups and the O 78 ,O 88 ,O 2 ,O 45 ,O 53 and O 145 serogroups were predominant.These E.coli were extensively drugs-resistance and all of the60strains of pathogenic E.coli had multi-antibiogram.Strains of O 78 ,O 88 and O 2 were inactivated and used as the potential vaccines against chicken E.coli infection respectively.The results of challenge showed that chicks inoculated with the potential vaccines were protected from disease over80%when challenged by the same O serogroup strain.