| Kit和KitL在卵泡发育过程中的作用 |
| |
| 引用本文： | 左通,成佳兴.Kit和KitL在卵泡发育过程中的作用[J].黑龙江动物繁殖,2010,18(2):4-7. |
| |
| 作者姓名： | 左通 成佳兴 |
| |
| 作者单位： | 东北农业大学,生命科学学院,黑龙江,哈尔滨,150030 |
| |
| 摘 要： | 在卵泡内,卵母细胞及其周围的颗粒细胞之间的旁分泌作用对哺乳动物的卵子发生和卵泡发育是非常重要的。研究表明颗粒细胞衍生的KitL(Kitligand,stem cell factor,SCF)与卵母细胞和膜细胞产生的Kit的相互作用在PGCs迁移和增殖、卵泡发育过程中有重要的作用。本文重点阐述了由KitL通过Kit激活的PI3K(phosphatidylinositol 3-kinase,磷脂酰肌醇-3-激酶)通路,它对卵母细胞生长、凋亡和卵泡早期发育起重要的调节作用。
|
| 关 键 词： | KitL Kit PGCs迁移 卵泡发育 P13K通路 |
Effects of Kit and KitL for Follicular Development |
| |
| ZUO Tong,CHENG Jia-xing.Effects of Kit and KitL for Follicular Development[J].Heilongjiang Journal of Animal Reproduction,2010,18(2):4-7. |
| |
| Authors: | ZUO Tong CHENG Jia-xing |
| |
| Institution: | (College of Life Science, Northereast Agricultural University, Haerbin 150030, China) |
| |
| Abstract: | Within the follicle,paracrine interactions between the oocyte and surrounding granulosa cells are critical for mammalian oogenesis and follicular development.Studies have revealed that interaction of granulosa cellderived KitL （Kit ligand,stem cell factor,SCF） with oocyte and theca cell-derived Kit is important for PGCs immigration and proliferation,follicular development.We predominantly elucidates PI3K signaling pathway,which is activated by KitL via Kit,is crucial for oocyte growth, apoptosis and follicle early development. |
| |
| Keywords: | KitL Kit |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
