| 宫内发育迟缓仔猪胎盘血管发育的分子机制及其营养调控 |
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| 引用本文： | 朱佳丽,李元晓,周汉林,李旺.宫内发育迟缓仔猪胎盘血管发育的分子机制及其营养调控[J].动物营养学报,2022,34(2):727-735. |
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| 作者姓名： | 朱佳丽 李元晓 周汉林 李旺 |
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| 作者单位： | 河南科技大学动物科技学院,洛阳 471000;中国热带农业科学院热带作物品种资源研究所,海口 571101 |
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| 基金项目： | 中国热带农业科学院基本科研业务费专项资金(1630032021004)。 |
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| 摘 要： | 宫内发育迟缓(IUGR)降低仔猪存活率和生长性能,给养猪业带来严重经济损失。如何有效降低IUGR仔猪的出生,一直是行业关注的科学问题。胎盘是一个高度血管化的器官,其血管生成异常会阻碍氧气和营养物质的正常运输,导致胎盘无法正常向胎儿提供足够的营养物质,这可能是引起仔猪IUGR的重要因素。鉴于胎盘血管在胎猪生长过程中扮演的重要角色,本文综述了胎盘血管生成在胎猪发育中的作用以及调控胎盘血管发育的营养因素,有助于进一步认识IUGR仔猪发生的分子机制,为降低IUGR仔猪的发生提供新的营养调控靶点。
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| 关 键 词： | 宫内发育迟缓 胎盘 血管生成 营养调控 母猪 |
Molecular Mechanism of Placental Vascular Development in Intrauterine Growth Retardation Piglets and Its Nutritional Regulation |
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| ZHU Jiali,LI Yuanxiao,ZHOU Hanlin,LI Wang.Molecular Mechanism of Placental Vascular Development in Intrauterine Growth Retardation Piglets and Its Nutritional Regulation[J].Acta Zoonutrimenta Sinica,2022,34(2):727-735. |
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| Authors: | ZHU Jiali LI Yuanxiao ZHOU Hanlin LI Wang |
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| Institution: | (College of Animal Science and Technology,Henan University of Science and Technology,Luoyang 471000,China;Tropical Crop Germplasm Research Institute,Chinese Academy of Tropical Agricultural Sciences,Haikou 571101,China) |
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| Abstract: | Intrauterine growth retardation(IUGR)can reduce the survival rate and growth performance of piglets and cause tremendous economic losses to the pig industry. How to effectively reduce the birth of IUGR piglets has always been a scientific issue of concern. Placenta is a highly vascularized organ. Abnormal placental angiogenesis hinders the normal transportation of oxygen and nutrients,leading to the placenta fail to provide enough nutrients to the fetus,which might be an important contributing factor to the occurrence of IUGR piglets.Given the important role of placental blood vessels in the growth of fetus,this article reviewed the role of placental angiogenesis in the development of fetal pigs and the nutritional factors that regulated the development of placental blood vessels,which will help to further understand the molecular mechanism of IUGR piglets and provide nutritional regulation strategies for decreasing the occurrence of IUGR piglets.Chinese Journal of Animal Nutrition,2022,34(2):727-735] |
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| Keywords: | IUGR placenta angiogenesis nutrition regulation sows |
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