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复方中药软膏剂的透皮效果研究
引用本文:张少华,任丽琴,包永占,秦建华,史万玉,钟秀会.复方中药软膏剂的透皮效果研究[J].动物医学进展,2010,31(1):58-62.
作者姓名:张少华  任丽琴  包永占  秦建华  史万玉  钟秀会
作者单位:河北农业大学动物科技学院,河北保定,071001
基金项目:国家“十一五”科技支撑计划(2006BAD04A10-42008BADB4B02);;河北省重大技术创新专项计划项目(07227146Z-4)
摘    要:为评价中药复方软膏剂透皮效果,筛选最佳组方,以中药软膏剂中绿原酸成分为标记物,应用高效液相色谱法(HPLC)测定透过液中绿原酸的含量,评价不同的中药剂型和不同的透皮促渗剂对中药软膏剂透皮效果的影响。结果表明,中药超微粉直接入药并以含45 g/L冰片+45 mL/L氮酮作为促渗剂效果最佳。

关 键 词:中药  软膏剂  高效液相色谱法

Effect of Herbal Compound Ointment on Percutaneous Absorption
ZHANG Shao-hua,REN Li-qin,BAO Yong-zhan,QIN Jian-hua,SHI Wan-yu,ZHONG Xiu-hui.Effect of Herbal Compound Ointment on Percutaneous Absorption[J].Progress In Veterinary Medicine,2010,31(1):58-62.
Authors:ZHANG Shao-hua  REN Li-qin  BAO Yong-zhan  QIN Jian-hua  SHI Wan-yu  ZHONG Xiu-hui
Institution:College of Animal Science and Technology;Agricultural University of Hebei;Baoding;Hebei;071001;China
Abstract:This study evaluated the effects of Chinese herbal compound transdermal ointment,screened the best formula.With chlorogenic acid as marker,the high performance liquid chromatography(HPLC) was used to determinate the content of chlorogenic acid in permeate liquid.The transdermal effects of different Chinese medicine formulations and different traditional Chinese medicine transdermal penetration enhancers on the traditional Chinese medicine ointment.The results indicated that the effect of traditional Chinese...
Keywords:traditional Chinese medicine  ointment  high-performance liquid chromatography  
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