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川楝素对妊娠小鼠子宫组织中CD4+/CD8+T细胞和F4/80+巨噬细胞的影响
引用本文:张建楼,黄军,钟秀会.川楝素对妊娠小鼠子宫组织中CD4+/CD8+T细胞和F4/80+巨噬细胞的影响[J].动物医学进展,2011,32(3):86-90.
作者姓名:张建楼  黄军  钟秀会
作者单位:河北农业大学中兽医学院,河北定州,073000
摘    要:为探讨CD4+、CD8+ T淋巴细胞和F4/80+巨噬细胞在流产发生机制中的意义,研究中药单体成分川楝素诱导小鼠流产的作用及机理,本试验给妊娠5 d小鼠连续3 d腹腔注射不同剂量的川楝素溶液,对照组以等量的蒸馏水代替,于妊娠9 d处死.在给药后发现随着注射川楝素剂量的增加,小鼠的流产率逐渐上升,CD4+、CD8+ T淋...

关 键 词:川楝素  CD4+  T淋巴细胞  CD8+  T淋巴细胞  F4/80+巨噬细胞

Effects of Toosendanin on Contents of CD4~+,CD8~+ T Lymphocytes and F4/80~+ Macrophage in Uterus of Pregnant mice
ZHANG Jian-lou,HUANG Jun,ZHONG Xiu-hui.Effects of Toosendanin on Contents of CD4~+,CD8~+ T Lymphocytes and F4/80~+ Macrophage in Uterus of Pregnant mice[J].Progress In Veterinary Medicine,2011,32(3):86-90.
Authors:ZHANG Jian-lou  HUANG Jun  ZHONG Xiu-hui
Institution:ZHANG Jian-lou,HUANG Jun,ZHONG Xiu-hui(College of Traditional Chinese Veterinary Medicine,Agricultural University of Hebei,Dingzhou,Hebei,073000,China)
Abstract:The experiment was conducted to explore the abortion effect and mechanism induced by Chinese herbal medicine component toosendanin,and study the T CD4+,CD8+ T lymphocytes and F4/80+ macrophages in the significance of abortion mechanism.The pregnant mice were injected intraperitoneaslly by different doses of toosendanin at day 5,6,7.CD4+,CD8+ T lymphocytes and F4/80+ macrophages were tested by immunohistochemistry.The data suggested that injection of toosendain could gradually increase the mice's abortion ra...
Keywords:toosendanin  CD4  lymphocyte  CD8  lymphocyte  F4/80  macrophage  
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