鹿皮蝇蛆对驯鹿抗氧化能力的影响

为了探讨驯鹿鹿皮蝇蛆对驯鹿机体氧化应激的影响,分别对鹿皮蝇蛆感染组和未感染组驯鹿血清中的总超氧化物歧化酶(T-SOD)、一氧化氮(NO)、谷胱甘肽过氧化物酶(GSH-Px)、丙二醛(MDA)、羟自由基(.OH)及总抗氧化能力(T-AOC)进行测定。结果表明鹿皮蝇蛆感染组血清中T-SOD、T-AOC活性、抑制.OH能力及NO含量极显著低于未感染组(P<0.01),血清中GSH-Px活性显著低于未感染组(P<0.05);血清中MDA含量极显著高于未感染组(P<0.01)。说明驯鹿感染鹿皮蝇蛆后,机体清除自由基能力降低,自由基在机体内大量蓄积,导致机体产生氧化应激反应。

The Effects of Hypoderma diana Larvae on Antioxidant Ability in Reindeers

In order to investigate the influence of reindeer deer skin myiasis on oxidative stress in vivo,the concentrations of T-SOD,NO,GSH-Px,MDA,·OH and T-AOC in sera,which were from the reindeers with or without Hypoderma diana larvae,were determined,respectively.The results showed that the activities of T-SOD,T-AOC,the capacity of inhibiting·OH and the concentrations of NO in serum were significantly lower than that in the control group(P<0.01);the GSH-Px activity of serum was also significantly lower than that in the control group(P<0.05);the activity of ·OH and the concentrations of MDA were extremely significantly higher than the control group(P<0.01).So we can conclude that,the free radical scavenging capacity was decreased,and lots of free radical were accumulated in serum,which can cause oxidative stress reaction in the reindeers infected with Hypoderma diana larvae.