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产气荚膜梭菌肠毒素的致病机理研究进展
引用本文:文其乙,刘秀梵.产气荚膜梭菌肠毒素的致病机理研究进展[J].动物医学进展,2002,23(2):17-18,32.
作者姓名:文其乙  刘秀梵
作者单位:扬州大学农业部畜禽传染病学重点开放实验室,江苏 扬州 225009
摘    要:产气荚膜梭菌是一种重要的人兽共患病的病原体,可引起人的食物中毒和抗生素相关腹泻,产气荚膜梭菌肠毒素是该菌的一个非常重要的致病毒素,在引起人的胃肠疾病方面起着关键性的作用,本文对产气荚膜梭菌肠毒素产生、细胞毒性和组织学作用以及在胃肠粘膜上造成损伤的致病分子机理等方面的研究内容进行论述。

关 键 词:产气荚膜梭菌  肠毒素  致病机理  研究进展
文章编号:1007-5038(2002)02-0017-03

Research Progress in Pathogenic Mechanism of Clostridium Perfingens Enterotoxin
WEN Qi,yi.Research Progress in Pathogenic Mechanism of Clostridium Perfingens Enterotoxin[J].Progress In Veterinary Medicine,2002,23(2):17-18,32.
Authors:WEN Qi  yi
Abstract:Clostridium perfringens has long been recognized as a significant cause of both histotoxic and gastrointestinal disease in humans and domestic animals. Clostridium perfringens enterotoxin(cpe) is a virulent factor as an important contributor to gastrointestinal symptom of Clostridium perfringens food poisoning and antibiotic associated diarrhea. This brief review is intended to provide on current research of formation mode of action and the pathogenic mechanism of cpe in human gastrointestinal disease.
Keywords:clostridium perfringens  enterotoxin  pathogenic mechanism  
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