| 两个中等毒力IBDV疫苗免疫鸡对超强毒攻毒的保护试验 |
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| 引用本文： | 孙淑红,崔治中,刘思当,商营利.两个中等毒力IBDV疫苗免疫鸡对超强毒攻毒的保护试验[J].动物医学进展,2003,24(6):112-114. |
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| 作者姓名： | 孙淑红 崔治中 刘思当 商营利 |
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| 作者单位： | 山东农业大学动物科技学院,山东泰安,271018 |
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| 基金项目： | 国家自然科学基金重大项目 (# 398932 90 )资助 |
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| 摘 要： | 应用 SPF鸡分别比较研究了两个国内厂家生产的中等毒力 IBDV疫苗接种后对法氏囊和胸腺的影响和对超强毒 GX-8/99攻毒后的免疫保护力。结果表明 ,用于试验的两个中等毒力疫苗虽然在 SPF鸡可引起法氏囊和胸腺不同程度的萎缩 ,但确实能够 1 0 0 %保护已经免疫的SPF鸡免于超强毒 IBDV人工感染造成的死亡 ,而且 ,还能减缓和预防超强毒感染合并诱发的法氏囊的炎症、出血和变性。从而说明 ,在不受母源抗体干扰条件下 ,中等毒力的 IBDV疫苗能诱发对超强毒 IBDV中国株 GX-8/99攻毒的有效免疫保护力。
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| 关 键 词： | 鸡传染性法氏囊病毒 免疫保护力 人工感染 |
| 文章编号： | 1007-5038(2003)06-0112-03 |
| 修稿时间： | 2003年4月25日 |
Protective Efficiency Against vvIBDV in SPF Chickens Vaccinated with 2 Cimmercial Vaccines of Medium Vialence |
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| SUN Shu-hong,CUI Zhi-zhong,LIU Si-dang,SHANG Ying-li.Protective Efficiency Against vvIBDV in SPF Chickens Vaccinated with 2 Cimmercial Vaccines of Medium Vialence[J].Progress In Veterinary Medicine,2003,24(6):112-114. |
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| Authors: | SUN Shu-hong CUI Zhi-zhong LIU Si-dang SHANG Ying-li |
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| Abstract: | To understand of the current commercial vaccine could also protect chickens fromvvIBDV challenges,two vaccines A and B were tested and compared for their protective immune efficacy in SPF chickens against vvIBDV strain GX8/99. The results indicated that both commercial vaccines protected mothernal antibody-free chickens very effectively against GX8/99 challenge. But both vaccine theselves also induce atrophy of the bursa and thymuses. |
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| Keywords: | Infectious bursa disease virus immune protective efficiency challenged |
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