| 精子介导外源DNA转移的研究进展 |
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| 引用本文： | 李碧春,钱菊汾.精子介导外源DNA转移的研究进展[J].动物医学进展,2000,21(4):13-17. |
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| 作者姓名： | 李碧春 钱菊汾 |
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| 作者单位： | 扬州大学畜牧兽医学院,扬州 |
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| 基金项目： | 江苏省自然科学基金项目!( BK970 75) |
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| 摘 要： | 精子因在受精过程中的独特作用，而被认为是转移外源ＤＮＡ的理想载体。本文对精子作载体进行转基因动物制作的方法、外源ＤＮＡ与精子作用的分子机制、导入动物个体或胚胎的外源ＤＮＡ的存在形式、影响精子与外源ＤＮＡ结合的因素进行了论述，并对精子作为载体的研究方向和发展前景给予了预测。
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| 关 键 词： | 精子载体 转基因 进展 DNA转移 |
Research Advance of Transducing Foreign DNA Through Sperm |
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| LI Bi chun ,QIAN Ju fen.Research Advance of Transducing Foreign DNA Through Sperm[J].Progress In Veterinary Medicine,2000,21(4):13-17. |
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| Authors: | LI Bi chun QIAN Ju fen |
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| Institution: | LI Bi chun 1,QIAN Ju fen 2 |
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| Abstract: | Due to sperm has special function which has been thought as ideal vector as transducing foreign DNA.In this review we introduced and assessed the recent advance in transducing gene through sperm,i.e.make method of transgenic animal,molecular mechanism of interact sperm and foreign DNA,foreign DNA existing form of introducing animal or embryo,factor of effect on integration of sperm and foreign DNA,and forecasting the development tendency of sperm as vector introducing gene into animal. |
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| Keywords: | spermatozoon vector transgene progre |
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