Molecular characterization of the equine herpesvirus 1 strains RacL11 and Kentucky D |
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| Authors: | Ghanem Yasser M Ibrahim El-Sayed M Yamada Souichi Matsumura Tomio Osterrieder Nikolaus Yamaguchi Tsuyoshi Fukushi Hideto |
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| Institution: | Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, Yanagido, Gifu, Japan. |
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| Abstract: | The pathogenicities of RacL11 and Kentucky D strains of equine herpesvirus 1 in the hamster infection model are different from those of Ab4p and the Japanese isolates. Virus genome restriction fragment length polymorphism analysis and sequence comparison of an intergenic region, glycoproteins and tegument genes showed higher conservation but with some strain-specific differences. These results indicate that point nucleotide differences in RacL11 and Kentucky D might be responsible for their pathogenicity in rodent models. |
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