Molecular epidemiological analysis of bat rabies viruses in Brazil |
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| Authors: | Kobayashi Yuki Sato Go Shoji Youko Sato Tetsuo Itou Takuya Cunha Elenice M S Samara Samir I Carvalho Adolorata A B Nociti Darci P Ito Fumio H Sakai Takeo |
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| Institution: | Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, Nihon University, Kanagawa, Japan. |
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| Abstract: | A molecular epidemiological analysis was performed in 19 rabies viruses (RVs) isolated from haematophagous, frugivorous and insectivorous bats, in Sao Paulo, Brazil. The authors carried out RT-PCR for amplification of the RV nucleoprotein (N) gene, and determined 1,335 nucleotide sequences of N gene by direct sequencing method. Phylogenetic analysis, which was based on the N gene of Brazilian RV isolates identified presently and previously, revealed that RVs isolated from bats were genetically divided into four lineages had a tendency to depend on the host bat species. The first lineage consisted mainly of haematophagous bat (Desmodus rotundus) isolates, including frugivorous bat (Artibeus spp.) isolates. Other three lineages consisted of insectivorous bat isolates; mainly Eptesicus spp., Molossus spp. and Nyctinomops spp. isolates, respectively. These results indicate a possibility of that there are bat species-specific RV variants in Brazil. |
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