MNC驱饲料铅对猪免疫和抗氧化性能的影响

以纳米蒙脱石（MNC）为吸附材料,重金属铅为吸附对象,以＂杜长大＂三元杂交猪为试验动物,研究了MNC驱铅对生长肥育猪机体免疫与抗氧化性能的影响。免疫学指标测定结果表明,与10mg/kg铅组比较,10mg/kg铅＋0.5%MNC组猪的胸腺、脾脏系数分别减少了27.97%（P〈0.01）、12.37%（P〈0.05）,T-淋巴细胞转化力、血清IgG、IgM水平分别提高了17.89%（P〈0.05）、16.20%（P〈0.05）、14.46%（P〈0.05）。试验各组的IgA水平均未发生显著性变化（P〉0.05）。抗氧化能力研究表明,与对照组相比,加MNC组猪血清与肝脏中MDA含量显著降低（P〈0.05）,CTA、SOD、GSH-Px活力均显著提高（P〈0.05）;与10mg/kg铅组比较,添加10mg/kg铅＋0.5%MNC组猪血清和肝脏中MDA含量明显下降（P〈0.05）,CTA、SOD、GSH-Px活力明显上升（P〈0.05）。此外,饲料中添加MNC后显著提高了猪肝脏中MT、K＋,Na＋-ATPase和Ca2＋,Mg2＋-ATPase酶活（P〈0.05）。结果表明,MNC能有效吸附饲料中的铅,阻断铅经消化道进入动物体内,改善猪的免疫与抗氧化性能。

Influences of montmorillonite nanocomposite as a Pb-sorbent on immunity and antioxidant capacity in pigs

Ninety-six pigs（Duroc×Landrace×Yorkshire） were randomly divided into four groups,each of which was replicated three times with eight pigs.The groups received the same basal diet supplemented with 0,0.5%MNC,10 mg/kg Pb and 10 mg/kg Pb＋0.5%MNC,respectively.Results showed Pb increased lipid peroxides level,thymus and spleen index,reduced ConA stimulation index of lymphocyte,IgG and IgM in serum and liver,along with a concomitant decrease in the activities of superoxide dismutase,catalase and glutathione peroxidase in liver,but in reverse while MNC was added into the diet.Moreover,the activities of hepatic MT,K＋,Na＋-ATPase and Ca2＋,Mg2＋-ATPase were also significantly reduced when fed diets supplemented with MNC.These results indicated that MNC is possible to improve the immunity and antioxidant capacity of pigs as a potential sorbent in Pb-contaminated feed.