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法氏囊活性肽对新城疫弱毒疫苗免疫效果影响的研究
引用本文:张秀根,范琳,蒋贻海,范根成,王川庆,董永毅,陈溥言,蔡宝祥.法氏囊活性肽对新城疫弱毒疫苗免疫效果影响的研究[J].中国预防兽医学报,1998(6).
作者姓名:张秀根  范琳  蒋贻海  范根成  王川庆  董永毅  陈溥言  蔡宝祥
作者单位:南京农业大学动物医学院,郑州牧业工程高等专科学校,农业部动检所
摘    要:本研究通过给鸡两次注射法氏囊活性肽后,接种新城疫弱毒疫苗,观察法氏囊活性肽对新城疫弱毒疫苗免疫效果的影响,结果表明:纯化的法氏囊活性肽能够提高新城疫弱毒疫苗所诱导产生的血清抗体水平,试验组比对照组平均高1~2个滴度;使血清母源新城疫抗体水平维持较高水平;促进法氏囊的生长发育,对抗传染性法氏囊弱毒疫苗(IBD)对法氏囊的损伤,和(或)促进损伤后的法氏囊的修复,对脾脏的生长发育没有影响。

关 键 词:法氏囊活性肽  法氏囊指数  脾脏指数  新城疫弱毒疫苗

the Affect of Bursin on Immunological Effects of Live Vaccine of Newcastle Disease
ZHANG Xiugen et al.the Affect of Bursin on Immunological Effects of Live Vaccine of Newcastle Disease[J].Chinese Journal of Preventive Veterinary Medicine,1998(6).
Authors:ZHANG Xiugen
Abstract:After two times injection of Bursin,NDV live vacccine was applyed to chickens,the results showed that the Bursin can enhance the level of serum antibody against NDV induced by ND attenuated live vaccine,the expermental groups higher than control about 1.5 2 titers averagely.It can maintain the maternal serum antibody against NDV at high level.The Bursin can also promote the Bursa of Fabricius growth,alleviate the lesions of IBD live vaccine to Bursa of Fabricius and/or promotingg the repairation to the lesions.the Bursin has no effectt on spleen growth.
Keywords:Bursin  Index of bursa of fabricius  Index of spleen  Attenuated live vaccine
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