| 番鸭呼肠孤病毒诱导雏番鸭免疫器官细胞凋亡的研究 |
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| 引用本文： | 陈志胜,马春全,卢玉葵,肖静芸.番鸭呼肠孤病毒诱导雏番鸭免疫器官细胞凋亡的研究[J].中国预防兽医学报,2005,27(6):457-458. |
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| 作者姓名： | 陈志胜 马春全 卢玉葵 肖静芸 |
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| 作者单位： | 佛山科技学院,广东,南海,528231 |
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| 摘 要： | 以番鸭呼肠孤病毒腿部肌肉接种10龄健康雏番鸭,复制番鸭"花肝病",并研究其不同时期诱导免疫器官细胞凋亡的能力.结果表明,雏番鸭在感染病毒后的12 h、24 h、48 h、72 h、144 h均能观察到胸腺、脾脏、法氏囊细胞凋亡的典型形态学变化,在12～24 h达到高峰,72 h后逐渐降低.由此可知,雏番鸭呼肠孤病毒对雏鸭免疫器官的细胞凋亡具有诱导作用.揭示该病毒致病机理与淋巴细胞凋亡从而引起的免疫抑制相关.
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| 关 键 词： | 番鸭呼肠孤病毒 雏番鸭 细胞凋亡 |
| 文章编号： | 1008-0589(2005)06-0457-02 |
| 收稿时间： | 2004-08-18 |
| 修稿时间： | 2004年8月18日 |
Apoptosis inducted by the muscovy duck reovirus infection in young ducks |
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| CHEN Zhi-sheng,MA Chun-quan,LU Yu-kui,XIAO Jing-yun.Apoptosis inducted by the muscovy duck reovirus infection in young ducks[J].Chinese Journal of Preventive Veterinary Medicine,2005,27(6):457-458. |
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| Authors: | CHEN Zhi-sheng MA Chun-quan LU Yu-kui XIAO Jing-yun |
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| Institution: | Foshan College of Science and Technology, Nanhai 528231, China |
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| Abstract: | Apoptosis of immtme organs in young ducks infected with MDRV was demonstrated. The result showed that intense apoptosis-specific signal was detected in immune organ at 12 h,24 h,48 h,72 h, 144 h after injection of MDRV. It kept short time and reached its peak at 12 h to 24 h. This suggest that the pathological mechanism of MDRV appears to be related to the immune restraint resulted in apoptosis of lymphocyte. |
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| Keywords: | muscovy duck reovirus(MDRV) muscovy duck apoptosis |
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