鸡产蛋下降综合症油乳剂灭活苗的免疫及攻毒保护试验

对应用当地分离病毒株研制的鸡产蛋下降综合症系列油乳剂灭活苗进行了免疫试验。结果表明，免疫后，鸡产蛋下降综合症（ＥＤＳ７６）油乳剂灭活苗、鸡新城疫（ＮＤ）－产蛋下降综合症二联油乳剂灭活苗及鸡新城疫－鸡传染性支气管炎（ＩＢ）－产蛋下降综合症三联油乳剂灭活苗免疫组的血清ＥＤＳ７６ＨＩ抗体迅速上升，维持４个月后仍在６．８－８（ｌｏｇ２）以上，并且能够抵抗强毒的攻击。证明所研制的ＥＤＳ７６油苗、ＮＤ－ＥＤＳ７６二联油苗、ＮＤ－ＩＢ－ＥＤＳ７６三联油苗对ＥＤＳ７６具有良好的免疫作用，能够抵抗ＥＤＳ７６强毒的攻击并产生高而持久的血清ＨＩ抗体。此外，对ＮＤ－ＥＤＳ７６二联苗、ＮＤ－ＩＢ－ＥＤＳ７６三联苗免疫组的血清ＮＤＨＩ抗体测定结果表明，上述二联苗、三联苗能产生与接种ＮＤ油苗一样良好的ＮＤ免疫效果，在免疫后１３０天时，其血清ＨＩ抗体仍高达９－１１（ｌｏｇ２）以上，与对照组有极显著的差异

Immunization with Oil Emulified Inactivated Vaccine for Egg Drop Syndrome and Challenge Protection Experiment

An oil emusified inactivated vaccine for egg drop syndrome (EDS) was developed using local strain and vaccination experiments were conducted. The results indicated that HI titers of EDS antibodies were raised rapidly in chickens immunized with oil emulsified inactivatod vaccine of EDS, binary vaccine of ND and EDS and tri vaccine of ND, IB and EDS, remained over 6.8-8 log2 for more than 4 months and could resist virulent virus challenge. In addition the HI titers of ND and IB remained over 9-11 log2 130 days after immunization with the binary or trivaccines.