| J亚群禽白血病病毒与禽网状内皮增生症病毒共感染对肉鸡生长和免疫功能的抑制作用 |
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| 引用本文： | 王建新,崔治中,张纪元,王增福,陈本龙,王锡乐.J亚群禽白血病病毒与禽网状内皮增生症病毒共感染对肉鸡生长和免疫功能的抑制作用[J].中国兽医学报,2003,23(3):211-213. |
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| 作者姓名： | 王建新 崔治中 张纪元 王增福 陈本龙 王锡乐 |
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| 作者单位： | 山东农业大学动物科技学院,山东,泰安,271018 |
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| 基金项目： | 国家自然科学基金资助项目(30040011,39893290(3)) |
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| 摘 要： | 1日龄网鸡感染J亚群禽白血病病毒(ALV-J)以及共感染禽网状内皮增生症病毒(REV)后,肉鸡生长发育明显受阻,体重增重明显下降(P＜0.05),法氏囊、胸腺明显萎缩(P＜0.05),在用新城疫疫苗免疫后,感染组血清中新城疫抗体效价显著低于对照组(P＜0.05);在ALV-J和REV共感染后,这种抑制作用更为明显(P＜0.01).ALV J单独感染后,鸡对传染性法氏囊病病毒(IBDV)弱毒疫苗免疫后的抗体反应与对照组没有明显差别,但ALV-J与REV的共感染可明显延缓鸡对IBDV弱毒疫苗免疫的抗体反应.
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| 关 键 词： | J亚群禽白血病病毒(ALV-J) 禽网状内皮增生病病毒(REV) 免疫抑制 共感染 |
| 文章编号： | 1005-4545(2003)03-0211-03 |
| 修稿时间： | 2002年11月11 |
Immunosuppression caused by avian leucosis virus of subgroup J and its coinfection with eticuloEndotheliosis virus in broilers |
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| WANG Jian xin,CUI Zhi zhong ,ZHANG Ji yuan,WANG Zeng fu,CHEN Ben long,WANG Xi le.Immunosuppression caused by avian leucosis virus of subgroup J and its coinfection with eticuloEndotheliosis virus in broilers[J].Chinese Journal of Veterinary Science,2003,23(3):211-213. |
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| Authors: | WANG Jian xin CUI Zhi zhong ZHANG Ji yuan WANG Zeng fu CHEN Ben long WANG Xi le |
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| Institution: | WANG Jian xin,CUI Zhi zhong *,ZHANG Ji yuan,WANG Zeng fu,CHEN Ben long,WANG Xi le |
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| Abstract: | When 1 day old broilers were infected with avian leukosis virus of subgroup J(ALV J) strain NX0101,the body weight was significantly reduced,atrophy of the bursa and thymus was detected,and antibody reaction to Newcastle disease virus vaccine was inhibited,while compared to the control birds(P<0 05).Such phenomena were even more serious when birds were co infected with ALV J strain NX0101 and reticuloendotheliosis virus(REV) strain SD9901 as compared to controls(P<0 01) or to birds infected with ALV J alone(P<0 05).ALV J infection alone gave no influence on reaction to IBDV vaccination in birds,but co infection of ALV J and REV apparently delayed antibody reactions to IBDV.This is the first report to demonstrate the immunosuppression of ALV J infection on broilers especially when co infcted with REV. |
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| Keywords: | ALV J REV immunosuppression co infection |
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