| 异丙酚麻醉对犬机体抗氧化功能的影响 |
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| 引用本文： | 高利,肖建华,高文学,王洪斌.异丙酚麻醉对犬机体抗氧化功能的影响[J].中国兽医学报,2010,30(4). |
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| 作者姓名： | 高利 肖建华 高文学 王洪斌 |
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| 作者单位： | 东北农业大学,动物医学院外科,黑龙江,哈尔滨,150030 |
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| 基金项目： | 黑龙江省博士后科研启动金资助项目 |
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| 摘 要： | 应用5%葡萄糖注射液稀释,稀释度1:5(2 g/L),犬异丙酚(4.25±0.5)mg/kg单次注射,麻醉维持剂量为0.4 mg/kg/分钟静脉输注,维持时闻为60 min.于麻醉前和麻醉后5、15、45、75、120 min分别采血离心,测定血清中丙二醛、一氧化氮、活性氧自由基、总抗氧化能力、超氧化物歧化酶(SOD)、谷胱甘肽(GSH).结果表明异丙酚麻醉对犬机体抗氧化能力具有保护作用.
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| 关 键 词： | 异丙酚 麻醉 总抗氧化能力 |
Effect of propofolum anesthesia on the function of organism antioxygen in dogs |
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| GAO Li,XIAO Jian-hua,GAO Wen-xue,WANG Hong-bin.Effect of propofolum anesthesia on the function of organism antioxygen in dogs[J].Chinese Journal of Veterinary Science,2010,30(4). |
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| Authors: | GAO Li XIAO Jian-hua GAO Wen-xue WANG Hong-bin |
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| Abstract: | Propofolum was diluted with 5% gl parenteral solution as 1 : 5 (2 g/L).Singly injected (4.25±0.5) mg propofolum by body per kg weight in dogs,the dose of maintenance of anesthesia is 0.4 mg/kg per rain by intrave-nous infusion,the maintain time was 60 minutes.Collected blood and centrifugated before and after anesthesia 5,15,45,75,120 min respectively,measure the malonaldehyde (MDA),nitrogen monoxidum (NO),oxyradical,total an-tioxygen ability,erythrocuprein (SOD) and Giutathione (GSH).The results showed the anaesthesia with propofolum had a protection for the function of organism antioxygen in dogs. |
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| Keywords: | propofolum anesthetize total antioxygen ability |
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