伊维菌素泼背剂对牦牛寄生虫的驱除效果试验

为选择适应于高寒牧区放牧牦牛大群驱除体内外寄生虫的理想荆型,在青海大通种牛场通过粪检选60头牦牛,随机分为3组,每组20头,试验1组用伊维菌素泼背荆接0.5 mg/kg体重剂量经背部皮肤浇泼给药,试验2组用伊维菌素注射剂按0.2 mg/kg体重剂量经皮下注射给药,试验3组为空白对照组.分析了三组不同寄生虫卵转率、虫卵减少率及驱虫率指标的变化,同时对药物的安全性进行了观察.结果试验1组消化道线虫虫卵转阴率、减少率分别为90%和99.1%,原圆科线虫幼虫转阴率、减少率分别为80%和92.8%;线虫成虫、寄生阶段幼虫的总计驱虫率分别为99.3%和98.8%;试验2组相应指标分别为90%和98.7%、80%和92.9%、99.4%和99.2%;1.2组对牛颚虱杀虫率均达100%,但对莫尼茨绦虫无效,对照组体内外寄生虫均无明显变化.表明伊维菌素泼背剂0.5 mg/kg剂量安全,驱虫效果可信,可在青海高寒地区牦牛体内外寄生虫驱虫工作中推广应用.

Anthelmintic Efficiency of Pour-sprinkling Ivermectin on Yak

The objective of present study was to select desirable formulation of ivermectin for expelling endo-,exo-parasites in the yak distributed in alpine grassland.60 yak were selected from Datong farm of Qinhai province,and randomly assigned to three group: The animals of group 1 were pour-sprinked ivermectin by 0.5mg/kg,animals of group 2 were subcutaneous injected ivermectin by 0.2mg/kg,the animals of group 3 were not given ivermectin.The changes of negative rates,decreasing rates and deworming rates of different parasites were analysed,meanwhile the safety of the medicine was investigated.In group 1,negative rate,decreasing rate of gastrointestinal nematode eggs,protostrongylus nematode larva was 90%/ 99.1% and 80%/92.8%,respectively.The average deworming rates were 99.3% and 98.8%,respectively.In group 2,negative rate,decreasing rate of gastrointestinal nematode eggs,protostrongylus nematode larva was 90%/98.7% and 80%/92.9%,respectively.The average deworming rates were 99.4% and 99.2%,respectively.Pour-sprinkling ivermectin can kill all Linnaeus,but can't kill Moniezia sp.This indicated that 0.5 mg/kg pour-sprinkling ivermectin was safety and efficiency,and can be applied in deworm of yak distributed in in alpine grassland.