| 环境内分泌干扰物对睾丸间质细胞功能的影响 |
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| 引用本文： | 杨炜蓉,王怡,孙燕.环境内分泌干扰物对睾丸间质细胞功能的影响[J].中国畜牧兽医,2012,39(5):157-159. |
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| 作者姓名： | 杨炜蓉 王怡 孙燕 |
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| 作者单位： | 西南大学动物科技学院, 重庆市牧草与草食家畜重点实验室, 重庆 400716 |
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| 基金项目： | 中央高校基本科研业务费专项项目，国家自然科学基金 |
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| 摘 要： | 近年来,环境内分泌干扰物(environmental endocrine disrupting chemicals,EDCs)对雄性动物的生殖毒性引起了广泛的关注。大量资料显示EDCs可引起雄性生殖发育障碍,如隐睾、尿道下裂、睾丸癌、精液品质不良等。作者就几种典型的EDCs对睾丸间质细胞分泌睾酮的影响机制作一综述。
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| 关 键 词： | EDCs 生殖发育障碍 作用机制 综述 |
| 收稿时间： | 2011-09-26 |
The Effects of Endocrine Disruptors on Leydig Cell Function |
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| YANG Wei-rong
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WANG Yi
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SUN Yan.The Effects of Endocrine Disruptors on Leydig Cell Function[J].China Animal Husbandry & Veterinary Medicine,2012,39(5):157-159. |
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| Authors: | YANG Wei-rong WANG Yi SUN Yan |
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| Institution: | Chongqing Key Laboratory of Forage ＆ Herbivore, College of Animal Science and Technology, Southwest University, Chongqing 400716, China |
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| Abstract: | During the past decades,the effects of endocrine disrupting compounds(EDCs) on animals and humans has caused wide attention.A large body of information have demonstrated that EDCs can cause the male reproductive developmental disorders such as cryptorchidism,hypospadias,testicular cancer,as well as decreased quality of semen.The aim of this paper is to give an overview of the published literature on the effects of EDCs on leydig cell function and steroidogenesis with particular focus on male reproduction and fertility. |
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| Keywords: | EDCs reproductive developmental disorders mechanism of action overview |
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