| 细胞病变观察法检测人参皂苷及其衍生物抗马立克氏病病毒的作用 |
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| 引用本文： | 褚秀玲,苏建青,韦旭斌.细胞病变观察法检测人参皂苷及其衍生物抗马立克氏病病毒的作用[J].中国畜牧兽医,2010,37(3):179-182. |
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| 作者姓名： | 褚秀玲 苏建青 韦旭斌 |
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| 作者单位： | （1.聊城大学农学院， 聊城 252000； 2.吉林大学畜牧兽医学院， 长春 130062） |
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| 基金项目： | 国家自然科学基金(30471272) |
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| 摘 要： | 为探讨人参皂苷及其衍生物体外抗马立克氏病病毒的作用机理,采用体外细胞培养法,在药物安全浓度范围内,测定人参皂苷及其衍生物对马立克氏病病毒(MDV)感染鸡胚成纤维细胞(CEF)的保护效果。结果显示,修饰前的人参皂苷和修饰后的衍生物7具有较好的抗病毒效果。表明人参皂苷和衍生物7可以减轻病毒对CEF细胞的损伤程度。
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| 关 键 词： | 细胞病变观察法 人参皂苷及其衍生物 马立克氏病病毒 |
Effect of Ginsenoside and its Derivatives against Marek's Virus by Cytopathic Observation |
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| CHU Xiu-ling,SU Jian-qing,WEI Xu-bin.Effect of Ginsenoside and its Derivatives against Marek''s Virus by Cytopathic Observation[J].China Animal Husbandry & Veterinary Medicine,2010,37(3):179-182. |
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| Authors: | CHU Xiu-ling SU Jian-qing WEI Xu-bin |
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| Institution: | （1.College of Agriculture,Liaocheng University, Liaocheng 252000,China； 2.College of Prologue and Veterinary, Jilin University, Changchun 130062,China） |
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| Abstract: | The objective of this paper is to study the antiviral mechanism of the ginsenoside and its derivatives against Marek's disease virus(MDV).In the safety concentration of drug,using in vitro cell culture method,the effect of ginsenoside and its derivatives on Marek's virus(MDV) infected chicken embryo fibroblasts(CEF) were determinated.The results showed that ginsenoside and derivative seven had good anti-virus effect.Ginsenoside and derivative seven reduce the damage of virus to the CEF cell. |
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| Keywords: | cytopathic observation ginsenoside and its derivatives Marek’s disease virus (MDV) |
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