Research Progress on Insulin-mimetic Effects of Selenium

During recent years，it has been found that selenium （Se） has insulin-mimetic effects on the promotion of glucose uptake into cells，glucose metabolism and signal transduction based on the relationship of Se and diabetes, but the effect dose of Se can only be obtained with nearly toxic doses and are not suitable for humans.This paper gives a brief review of research progress on insulin-mimetic effects of Se，in favor of an extensive study on the regulation mechanism of Se in glucose metabolism，so as to provide a reference for applying Se for regulation of disorders of glucose metabolism in stressed animals.