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Allergic Study of Ivermectin Microemulsion
Authors:XING Shou-ye  ZHOU Xu-zheng  LI Bing  NIU Jian-rong  WEI Xiao-juan  ZHANG Ji-yu
Institution:1.Key Laboratory of New Animal Drug Discovery, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730070, China;2. College of Veterinary Medicine, Gausu Agricultural University, Lanzhou 730050, China
Abstract:The study was aimed to observe the allergic reaction of ivermectin microemulsion injection on animals. Active systemic allergy test and passive cutaneous anaphylaxis test were carried out to study the allergic reaction of ivermectin microemulsion injection on Wistar rat and guinea pig, respectively, according to . The results showed that the allergic reaction of ivermectin microemulsion injection on Wistar rat and guinea pig were both negative. The study provided experiment evidences for the safety evaluation of ivermectin microemulsion.
Keywords:ivermectin microemulsion  guinea pig  rat  allergic test  
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