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| 金线莲多糖对免疫抑制小鼠脾淋巴细胞增殖及免疫器官的影响 | |
| 引用本文： | 许丹妮,李健,马玉芳,黄一帆.金线莲多糖对免疫抑制小鼠脾淋巴细胞增殖及免疫器官的影响[J].中兽医医药杂志,2011,30(3):15-17. |
| 作者姓名： | 许丹妮 李健 马玉芳 黄一帆 |
| 作者单位： | 1. 福建农林大学食品科学学院,福建福州,350002 2. 福建农林大学动物科学学院 3. 福建农林大学食品科学学院,福建福州,350002;福建农林大学动物科学学院 |
| 摘 要： | 目的：探讨金线莲多糖对免疫抑制小鼠脾淋巴细胞增殖及免疫器官的影响。方法：按大、中、小剂量给小鼠灌胃金线莲多糖，腹腔注射环磷酰胺（CY）建立免疫抑制模型；测定小鼠体重及胸腺、脾脏重量，计算胸腺、脾指数；采用MTT法检测脾淋巴细胞的增殖。结果：3个金线莲多糖剂量组小鼠的体重及免疫器官指数均低于空白组而高于模型组，脾淋巴细胞增殖均显著（P〈O．05）高于模型组。结论：金线莲多糖能提高免疫抑制小鼠体重及免疫器官指数，促进脾淋巴细胞增殖。 |
| 关 键 词： | 金线莲多糖 环磷酰胺 免疫抑制 脾淋巴细胞增殖 |
Effects of Anoectochilus formosanus polysaccharide on lymphocyte proliferation and immune organs of mice with immunological suppression |
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| XU Dan-ni,LI Jian,MA Yu-fang,HUANG Yi-fan.Effects of Anoectochilus formosanus polysaccharide on lymphocyte proliferation and immune organs of mice with immunological suppression[J].Journal of Traditional Chinese Veterinary Medicine,2011,30(3):15-17. | |
| Authors: | XU Dan-ni LI Jian MA Yu-fang HUANG Yi-fan |
| Institution: | XU Dan-ni,HUANG Yi-fan(College of Food Science,Fujian Agriculture and Forestry University,Fuzhou Fujian 350002,China) |
| Abstract: | Objective:To explore the effects of Anoectochilus formosanus polysaccharide on lymphocyte proliferation and immune organs of mice with immunological suppression.Methods:Different dosages of Anoectochilus formosanus polysaccharide were perfused to the mice and mice models with immunological suppression were developed with cyclophosphamide by intraperitoneal injection.The weight of the mice,thymus and spleen were measured,the thymus index and spleen index were calculated.The proliferation of spleen lymphocyte... |
| Keywords: | A noectochilus formosanus polysaccharide cyclophosphamide immunological suppression proliferation of spleen lymphocytes |
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