| 裙带菜膳食纤维对高脂血症大鼠体内内皮素-1水平的影响 |
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| 引用本文： | 许建平,肖红波.裙带菜膳食纤维对高脂血症大鼠体内内皮素-1水平的影响[J].中兽医医药杂志,2011,30(3):11-13. |
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| 作者姓名： | 许建平 肖红波 |
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| 作者单位： | 湖南农业大学动物医学院,湖南长沙,410128 |
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| 基金项目： | 湖南农业大学动物医学院基金项目，湖南农业大学青年基金项目 |
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| 摘 要： | 目的：研究裙带菜可溶性膳食纤维对体内内皮素－1水平的影响。方法：40只大鼠分为4组（n=10）：正常对照组、高脂模型组、膳食纤维低剂量组（5％）、膳食纤维高剂量组（10％）；经裙带菜可溶性膳食纤维处理8W后，检测血浆内皮素－l（ET－1）水平，并用RT－PCR检测内皮素－1（ET－1）mRNA表达水平。结果：裙带菜可溶性膳食纤维显著降低ET－1水平并伴随着（ET－1）mRNA表达下调。结论：裙带菜可溶性膳食纤维能降低高脂血症大鼠血浆ET－l的水平，这可能与ET－1mRNA表达水平的下调有关。
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| 关 键 词： | 裙带菜 可溶性膳食纤维 内皮素-1 大鼠 |
Effect of Undaria pinnatifida dietary fiber on endothelin-1 level in hyperlipemic rats |
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| XU Jian-ping,XIAO Hong-bo.Effect of Undaria pinnatifida dietary fiber on endothelin-1 level in hyperlipemic rats[J].Journal of Traditional Chinese Veterinary Medicine,2011,30(3):11-13. |
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| Authors: | XU Jian-ping XIAO Hong-bo |
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| Institution: | XU Jian-ping,XIAO Hong-bo(College of Veterinary Medicine,Hunan Agricultural University,Changsha Hunan 410128,China) |
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| Abstract: | Objective:To test the effect of Undaria pinnatifida soluble dietary fiber on e nitric oxide level in hyperlipemic rats.Methods:40 rats were divided into 4 groups(n=10):control group,hyperlipemic model group,low dose dietary fiber-treated group(5%) and high dose dietary fiber-treated group(10%).After treatment for 8 weeks,the content of plasma endothelin-1(ET-1) was determined.The protein expression of endothelin-1(ET-1) mRNA was measured using RT-PCR.Results:Undaria pinnatifida soluble dietary fiber treatme... |
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| Keywords: | Undaria pinnatifida soluble dietary fiber endothelin-1 rats |
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