中草药“杀虫补”防治鸡球虫病实验研究

中药"杀虫补"以杀虫燥湿、清热解毒遣药组方,主要由攻毒杀虫、去腐敛疮类药组成。实验结果表明,1%"杀虫补"组ACI为181.7,相对增重率达88.7%;0.5%"杀虫补"组ACI为173.4,相对增重率达82.4%;磺胺氯吡嗪钠组ACI为173.5,相对增重率达80.5%,表明"杀虫补"治疗鸡球虫病的效果确切,1%治疗剂量属高效杀虫药。用5%和10%剂量进行慢性毒性实验,未发现明显的中毒反应,但平均增重率分别为43.1%和32.0%,增重效果明显受到影响(P0.01),说明长期大剂量使用,会造成鸡的生长抑制。5 g/kg和3 g/kg剂量急性毒性实验表明,大剂量一次性使用不会造成鸡的死亡,但会抑制鸡的生长。以上实验结果表明,该中药组方对肉鸡球虫病具有治疗、预防以及增重的效果,按治疗剂量使用安全有效。

Prevention and treatment of chicken coccidiosis by using Chinese medicinal herb Shachongbu

In order to assess the effect of Chinese medicinal herb Shachonghu against coccidiosis in chicken, 135 chickens of 32-day-old were assigned to four groups, including Shachonghu, treatment group （n=60）. prevention group （n=30）, chronic and acute toxicity group （n=30） and blank control group （n=15）. The results showed that the anticoccidial index （ACI） was 181.7 and 173.4, relative weight-growth rate was 88.7% and 82.4% when 1% and 0.5% of Shachongbu was used against chickens coccidiosis, respectively. But in Sanziqiuchongfen control group, ACI and relative weight-growth rate was 173.5 and 80.5%, respectively, and the treatment effect was not as good as 1% of Shachongbu. In the prevention test, the average rate of weight increase in 0..5% and 1% of Shachongbu group was75.1% and 78.6% （P〈0.01）. which was 66.6% higher than that of the healthy control group. In the toxicity test, 5% and 10% dosage of Shachongbu had no toxic reaction, but the average rate of weight increase was decreased by 43.1% and 32.0%, respectively （P〈0.01）, which indicated that high dosage of Shachongbu could inhibit chickens growth. When the chickens were given Shachongbu at 5 g/kg or 3 g/ kg for 4 days, no chickens were found to die, but the average rate of weight increase was decreased by 11.9% and 14.7%, respectively （P〈0.01）. The results indicated that the herb Shachongbu composition could prevent and treat coccidiosis in chickens.