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猪口蹄疫○型合成肽疫苗诱导的免疫抗体的监测
引用本文:李儒曙,伍时达,冷和平,赵庆文,游淼,张健騑.猪口蹄疫○型合成肽疫苗诱导的免疫抗体的监测[J].广东畜牧兽医科技,2012(4):27-29.
作者姓名:李儒曙  伍时达  冷和平  赵庆文  游淼  张健騑
作者单位:珠海市动植物防疫监督检验中心;珠海经济特区农牧开发总公司;广东省农业科学院兽医研究所
摘    要:设3组猪群,首免和二免分别注射生理盐水1 mL、猪口蹄疫0型合成肽疫苗1 mL(说明书推荐免疫剂量)及猪口蹄疫0型合成肽疫苗3 mL(说明书推荐免疫剂量3倍量),二免28天后检测猪群的口蹄疫抗体,结果显示3组猪群的抗体合格率分别为33%、78%和100%,疫苗诱导的抗体水平达到农业部规定的动物强制免疫标准。

关 键 词:猪口蹄疫0型合成肽疫苗  抗体  监测

Surveillance on the immune antibodies against synthetic peptide vaccine for O type FMDV
Li Rushu,Wu Shida,Leng Heping,Zhao Qingwen,You Miao,Zhang Jianfei.Surveillance on the immune antibodies against synthetic peptide vaccine for O type FMDV[J].Guangdong Journal of Animal and Veterinary Science,2012(4):27-29.
Authors:Li Rushu  Wu Shida  Leng Heping  Zhao Qingwen  You Miao  Zhang Jianfei
Institution:1.Zhuhai Epidemic Prevention and Supervision Center for Animals and Plants,Zhuhai 519000,China;2.Zhuhai Development Corporation of Agriculture and Animal,Zhuhai 519000,China;3.Institute of Veterinary Medicine,Guangdong Academy of Agricultural Sciences,Guangzhou 510640,China)
Abstract:All the pigs were divided into three groups.One milliliter of physiological saline,one milliliter of synthetic peptide vaccine or three milliliters of synthetic peptide vaccine were injected to the pigs in each group separately for two times.The immune antibodies against FMDV were detected at 28 days later from the second immunization.The results showed that the antibody passing rates were 33%,78%or 100%separately.The antibody level induced by vaccines reached the compulsive immunity standard set by the Ministry of Agriculture.
Keywords:Synthetic peptide vaccine for O type FMDV  Antibody  Surveillance
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