QuEChERS-超高效液相色谱-串联质谱法测定玉米粉中41种农药残留

基于QuEChERS-超高效液相色谱-串联质谱 (UPLC-MS/MS)，建立了同时检测玉米粉中41种常见农药残留的分析方法。玉米粉样品经乙腈提取、QuEChERS方法净化后，采用UPLC-MS/MS检测分析。结果表明:在0.5~100 μg/L 范围内，41种待检农药质量浓度与对应的峰面积间均呈良好线性关系，决定系数均在 0.99以上；41种农药的定量限 (LOQ) 为 0.48~0.85 μg/kg；在0.01、0.1和1 mg/kg添加水平下，41种农药的平均回收率在74%~110%之间，相对标准偏差 (RSD) 在1.5%~12% (n = 5) 之间。该方法高效、快速、灵敏、准确，适用于玉米粉中多种农药残留的同时检测。

Determination of 41 pesticides in maize meal by QuEChERS and ultra-high performance liquid chromatography-tandem mass spectrometry

Based on QuEChERS and ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), a method for the simultaneous detection of 41 pesticide residues in maize meal was established. Maize meal samples were extracted with acetonitrile and analysed by UPLC-MS/MS after treated with QuEChERS approach. Good linearity was observed when the mass concentration of 41 pesticides ranged between 0.5 and 100 μg/L, with all of the determination coefficients higher than 0.99. Limit of quantitations (LOQs) of the pesticides ranged from 0.48 to 0.85 μg/kg. At the fortified levels of 0.01, 0.1, and 1 mg/kg, average recoveries of the 41 pesticides ranged between 74% and 110%, and the relative standard deviations (RSDs) were 1.5% to 12% (n = 5). This new method is efficient, fast, sensitive and accurate, which is suitable for the simultaneous detection of multiple pesticides in maize meal.