| 核磁共振法测定甲哌鎓原药的含量 |
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| 引用本文： | 魏泱,王晓莉,郭幸丽,刘晶晶.核磁共振法测定甲哌鎓原药的含量[J].农药科学与管理,2014,35(12):49-52. |
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| 作者姓名： | 魏泱 王晓莉 郭幸丽 刘晶晶 |
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| 作者单位： | 北京颖泰嘉和生物科技有限公司,北京,100192 |
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| 摘 要： | 采用定量核磁共振法建立了甲哌鎓原药的定量方法。以重水为溶剂,仲丁基脲为内标物,以化学位移分别在δ3.12的甲哌鎓甲基和δ1.10的仲丁基脲甲基的1H-NMR信号作为定量峰。以甲哌鎓与仲丁基脲定量峰的峰面积比(AS/AI)对甲哌鎓与仲丁基脲的质量比(WS/WI)进行线性回归,线性相关系数为0.999 9;重复测定同一批次原药含量,变异系数为0.28%。采用核磁共振波谱法对甲哌鎓进行定量分析,操作简便,测定速度快,准确度高。
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| 关 键 词： | 定量核磁共振法 甲哌鎓 仲丁基脲内标 |
Determination of the Content of Mepiquat Chloride by Quantitative Nuclear Magnetic Resonance Spectrometry |
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| Wei Yang,Wang Xiaoli,Guo Xingli,Liu Jingjing.Determination of the Content of Mepiquat Chloride by Quantitative Nuclear Magnetic Resonance Spectrometry[J].Pesticide Science and Administration,2014,35(12):49-52. |
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| Authors: | Wei Yang Wang Xiaoli Guo Xingli Liu Jingjing |
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| Institution: | ( Nutrichem Company Limited, Beijing 100192, China) |
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| Abstract: | A quantitative analytical method for Mepiquat chloride by nuclear magnetic resonance spectrometry was developed.The heavy water was used as solvent and 1-（sec-butyl） urea was used as internal standard.The methyl peak at 3.12 of Mepiquat chloride and the methyl peak at 1.10 of 1-（sec-butyl） urea were used for quantification.Linear regression of quantitative peak area ratio （AS/AI） versus mass ratio （WS/WI） of Mepiquat chloride to 1-（sec-butyl） urea yielded a correlation coefficient of 0.999 9.The variation coefficient within the same batch sample was 0.28％.This method could be used to determining the content of Mepiquat chloride quickly and accurately. |
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| Keywords: | quantitative nuclear magnetic resonance spectrometry mepiquat chloride 1-(sec-butyl) urea internal standard |
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