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Effect of Melia azedarach extract on the activity of NADPH-cytochrome c reductase and cholinesterase in insects |
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| Authors: | Michael Breuer Bruno HosteArnold De Loof SNH Naqvi |
| Institution: | a Zoological Institute, Laboratory for Developmental Physiology and Molecular Biology, Catholic University of Leuven, Naamsestraat 59, B-3000 Leuven, Belgium b Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Deh Tor, P.O. Box. 2407, Karachi 74600, Pakistan |
| Abstract: | The effect of Melia azedarach extract on the activity of NADPH-cytochrome c reductase and cholinesterase was studied in Spodoptera frugiperda. Larvae were fed an artificial diet containing fruit extract and their midgut was used for enzyme determination. As compared to the control, consumption of the extract containing diet resulted in a 31% inhibition of the cholinesterase activity and a 34% activation of the NADPH-cytochrome c reductase activity. In the cockroach Leucophaea maderae, the effect on reductase activity was even more pronounced (43%). |
| Keywords: | Melia azedarach Plant extract Plant insecticide Spodoptera frugiperda Leucophaea maderae NADPH-cytochrome c reductase Cholinesterase |
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