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离子液体[C8Mim]Cl对泥鳅毒性效应的研究
引用本文:燕帅国,南平,韩晨露,杜启艳,常重杰.离子液体[C8Mim]Cl对泥鳅毒性效应的研究[J].水生态学杂志,2012,33(5):119-122.
作者姓名:燕帅国  南平  韩晨露  杜启艳  常重杰
作者单位:河南师范大学生命科学学院,河南新乡,453007
基金项目:国家自然科学基金(3071666);河南师范大学博士基金(No.01046500120)
摘    要:以泥鳅(Misgurnus anguillicaudatus)为受试动物,采用急性毒性、遗传毒性及生理毒性试验,研究了C8Mim]Cl对生物体的毒性效应.结果表明,C8Mim] Cl对泥鳅有一定的毒性,其对泥鳅24h、48 h的LC50分别为324.13 mg/L、262.77mg/L,安全浓度为51.80 mg/L;各处理组的微核率均高于对照组(P<0.05),且随着处理浓度的升高和时间的推移,红细胞微核率都有明显的升高;处理组血清中的谷丙转氨酶(GPT)和谷草转氨酶(GOT)活力均明显高于对照组(P<0.05),且随离子液浓度升高以及时间的推移而增高;C8Mim] Cl对泥鳅有显著的毒性作用.

关 键 词:泥鳅  离子液体  毒性
收稿时间:2012/6/11 0:00:00
修稿时间:2012/6/11 0:00:00

A Study on the Toxicity Effect of [C8 Mim]Cl to Misgurnus anguillicaudatus
YAN Shuai guo,NAN Ping,HAN Chen lu,DU Qi yan and ChANG Zhong jie.A Study on the Toxicity Effect of [C8 Mim]Cl to Misgurnus anguillicaudatus[J].Journal of Hydroecology,2012,33(5):119-122.
Authors:YAN Shuai guo  NAN Ping  HAN Chen lu  DU Qi yan and ChANG Zhong jie
Institution:College of Life Sciences, Henan Normal University,College of Life Sciences, Henan Normal University,College of Life Sciences, Henan Normal University,College of Life Sciences, Henan Normal University and College of Life Sciences, Henan Normal University
Abstract:In this study, the toxicity effect of C8Mim]Cl to Loach (Misgurnus Anguillicaudatus) had been studied using the methods of acute toxicity test, genetic toxicity test, and the physical toxicity test. The results of above tests showed that: C8Mim]Cl had a certain toxicity effect to loach, and the LC50 of 24 h, 48 h were 324.13 mg/L, 262.77mg/L, and its safe concentration was 191.80 mg/L; the micronucleus rates of treatment groups were all higher than its control group, and there was significant difference (P<0.05) between the treatment groups and their control group; the GPT and GOT activity of blood serum in the treatment groups were significantly higher than its control group (P<0.05), and the activity of GPT and GOT became more and more higher with the increase of treating concentration and treating time of ion liquid. Conclusion: C8Mim]Cl had significant toxicity effect on loach.
Keywords:Loach (Misgurnus Anguillicaudatus)  [C8Mim]Cl  Micronucleus  GPT  GOT
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