| 紫色球海胆Tcf/lef基因的生物信息学分析 |
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| 引用本文： | 瞿飞,赵楠,焦传珍,孙淑红,刘小林.紫色球海胆Tcf/lef基因的生物信息学分析[J].水产科学,2008,27(1):32-35. |
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| 作者姓名： | 瞿飞 赵楠 焦传珍 孙淑红 刘小林 |
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| 作者单位： | 1. 西北农林科技大学,动物科技学院,陕西,杨陵,712100
2. 德州学院,生物系,山东,德州,253023 |
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| 基金项目： | 国家“863”高科技项目(2006AA10A411) |
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| 摘 要： | 利用生物信息学方法寻找与人类Ⅱ型糖尿病相关的Tcf7L2基因在紫色球海胆中的同源基因Tcf/lef,对该基因的序列、外显子信息、编码蛋白及其理化性质进行分析,并预测其编码蛋白的结构与功能,构建其同源基因的系统进化树,旨在为今后的研究提供一定的依据。
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| 关 键 词： | 紫色球海胆 Tcf/lef 生物信息学 |
| 文章编号： | 1003-1111（2008）01-0032-04 |
| 收稿时间： | 2007-06-23 |
| 修稿时间： | 2007-09-19 |
Bioinformatics Analysis of Tcf/lef Gene from Sea Urchin Strongylocentrotus purpuratus |
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| QU Fei,ZHAO Nan,JIAO Chuan-zhen,SUN Shu-hong,LIU Xiao-lin.Bioinformatics Analysis of Tcf/lef Gene from Sea Urchin Strongylocentrotus purpuratus[J].Fisheries Science,2008,27(1):32-35. |
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| Authors: | QU Fei ZHAO Nan JIAO Chuan-zhen SUN Shu-hong LIU Xiao-lin |
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| Abstract: | The sea urchin Strongylocentrotus purpuratus genome project had been completed and took a vital significance in life sciences.In this article,the bioinformatics was used to seek the homologous gene of Tcf 7L2 in the sea urchin which was involved in human Type 2 Diabetes.The sequence of Tcf/lef gene,exons,the Tcf/lef gene coding protein,Tcf/Lef,and its physical and chemical characteristics were determined.The phylogenetic tree for the homologous gene evolution was established,which will provide certain basis for the future research. |
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| Keywords: | sea urchin Strongylocentrotus purpuratus Tcf/lef bioinformatics |
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