Winter Field Trials of Enrofloxacin for the Control of Aeromonas salmonicida Infection in Salmonids |
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| Authors: | H-M Hsu P R Bowser J H Schachte Jr J M Scarlett J G Babish |
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| Institution: | Department of Avian and Aquatic Animal Medicine, College of Veterinary Medicine, Cornell University, Ithaca. New York 14853 USA;Fish Disease Control Unit. New York State Department of Environmental Conservation. 8314 Fish Hatchery Road, Rome, New York 13440 USA;Section of Epidemiology, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 USA;Department of Pharmacology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 USA |
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| Abstract: | The antimicrobial enrofloxacin (Baytril®, Bayer) was evaluated under field conditions in the winter months for treatment of clinical Aeromonas salmonicida infections in salmonids by feeding medicated diets. Two trials in which lake trout Salvelinus namaycush were treated with enrofloxacin at 10mg/kg per d for 10d resulted in reduced mortalities when compared to non-medicated controls. A third trial in which Atlantic salmon Salmo salar were treated required 20d for the fish to consume the 10d medicated ration, due to poor feeding. This resulted in an effective dose of 5mg/kg per d for 20d. In spite of the lower feeding activity, a reduction in mortalities in medicated fish was observed. Tissue concentrations of drug were in excess of minimum inhibitory concentrations of the drug for the A. salmonicida isolates tested. |
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